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          • Primary Antibodies ›
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          CD11a/CD18 Antibodies

          Antibodies that detect CD11a/CD18 can be used in several scientific applications, including Flow Cytometry, Functional Assay, Immunohistochemistry and Immunoprecipitation. These antibodies target CD11a/CD18 in Equine and Human samples. Our CD11a/CD18 monoclonal antibodies are... Antibodies that detect CD11a/CD18 can be used in several scientific applications, including Flow Cytometry, Functional Assay, Immunohistochemistry and Immunoprecipitation. These antibodies target CD11a/CD18 in Equine and Human samples. Our CD11a/CD18 monoclonal antibodies are developed in Mouse. Find the CD11a/CD18... Antibodies that detect CD11a/CD18 can be used in several scientific applications, including Flow Cytometry, Functional Assay, Immunohistochemistry and Immunoprecipitation. These antibodies target CD11a/CD18 in Equine and Human samples. Our CD11a/CD18 monoclonal antibodies are developed in Mouse. Find the CD11a/CD18 antibody that fits your needs. Choose from 1 of 3 CD11a/CD18 antibodies.

          Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop...
          Antibodies that detect CD11a/CD18 can be used in several scientific applications, including Flow Cytometry, Functional Assay, Immunohistochemistry and Immunoprecipitation. These antibodies target CD11a/CD18 in Equine and Human samples. Our CD11a/CD18 monoclonal antibodies are developed in Mouse. Find the CD11a/CD18 antibody that fits your needs. Choose from 1 of 3 CD11a/CD18 antibodies.

          Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

          Target Information

          CD11/CD18 (LFA-1) are beta 2-type integrins. The leukocyte integrins are a family of heterodimeric receptors that mediate divalent cation-dependent cellular adhesion reactions. T cells use integrins in essentially all of their functions. Integrins become active following signalling through other membrane receptors, which cause both affinity alteration and an increase in integrin clustering. The monoclonal antibody 24 recognizes a structural feature and is strictly dependent upon the presence of Mg2+. The epitope is located within, or in close proximity to, the three conserved cation binding domains and therefore a measure of Mg2+ bound to the leukocyte integrins and thus reflects functionally active molecules. The epitope can be induced on polymorphonuclear leukocytes and on monocytes. Glu173 and Glu175 of the beta(2) I domain are identified as critical for antibody 24 binding. The monoclonal antibody 24 inhibits monocyte-dependent, antigen specific T cell proliferation and IL-2- activated natural killer cell assays. The antibody does not interfere with mitogen-stimulated T cell proliferation. Furthermore the monoclonal antibody 24 prevents deadhesion of receptor/ligand pairs, possible locking leukocyte integrins in an active conformation.

          Synonyms

          antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; CD11 antigen-like family member A; CD11a; CD18; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; Complement receptor C3 subunit beta; integrin alpha L; integrin alpha-L; integrin beta chain, beta 2; integrin beta-2; integrin gene promoter; integrin subunit alpha L; integrin subunit beta 2; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGAL; ITGB2; LAD; LCAMB; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte cell adhesion molecule CD18; leukocyte function-associated molecule 1 alpha chain; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; MAC-1; MF17; MFI7

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          3 results
          Invitrogen
          CD11a/CD18 Monoclonal Antibody (24)
          Invitrogen
          CD11a/CD18 Monoclonal Antibody (24)
          Target
          Human
          Details
          Mouse Monoclonal
          Application
          IHC (F) Flow IP Functional
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # MA5-33356

          100 µg

          Invitrogen
          CD11a/CD18 Monoclonal Antibody (CVS9), FITC
          Invitrogen
          CD11a/CD18 Monoclonal Antibody (CVS9), FITC
          Target
          Horse
          Details
          Mouse Monoclonal
          Application
          Flow
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # MA5-28272

          100 µg

          Invitrogen
          CD11a/CD18 Monoclonal Antibody (CVS9), PE
          Invitrogen
          CD11a/CD18 Monoclonal Antibody (CVS9), PE
          Target
          Horse
          Details
          Mouse Monoclonal
          Application
          Flow
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # MA5-28273

          100 Tests

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