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          System Message

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          LOADING ...
          See other PSEN1 SIRNA Assays ›
          Gene Symbol:
          Psen1
          Gene Name:
          presenilin 1
          Gene Aliases:
          -
          Chromosome Location:
          Chr.6: 107169513 - 107220957 on Build Rnor_6.0
          UniGene ID:
          Rn.44440
          Species:
          Rat
          siRNA ID RSS307394
          Size 20 nmol
          Availability Made To Order
          Catalog # 1330001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Psen1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_019163.3 NP_062036.2 6 850
          XM_006240321.2 XP_006240383.1 8 1120
          XM_006240322.2 XP_006240384.1 8 1373
          GenBank mRNA BC070887.1 - 8 1046 7098018
          D82363.1 - 6 850
          D82578.1 - 6 850
          FQ231303.1 - 8 1068

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          autophagosome assembly
          negative regulation of transcription from RNA polymerase II promoter
          activation of MAPKK activity
          blood vessel development
          cell fate specification
          somitogenesis
          neuron migration
          positive regulation of receptor recycling
          negative regulation of protein phosphorylation
          positive regulation of protein phosphorylation
          heart looping
          hematopoietic progenitor cell differentiation
          T cell activation involved in immune response
          myeloid leukocyte differentiation
          neural retina development
          negative regulation of protein kinase activity
          protein glycosylation
          proteolysis
          membrane protein ectodomain proteolysis
          calcium ion transport
          mitochondrial transport
          cellular calcium ion homeostasis
          autophagy
          cellular response to DNA damage stimulus
          response to oxidative stress
          negative regulation of epidermal growth factor-activated receptor activity
          regulation of epidermal growth factor-activated receptor activity
          Notch signaling pathway
          Notch receptor processing
          brain development
          heart development
          learning or memory
          memory
          post-embryonic development
          protein transport
          L-glutamate transport
          choline transport
          synaptic vesicle targeting
          single organismal cell-cell adhesion
          protein processing
          cerebral cortex cell migration
          Cajal-Retzius cell differentiation
          dorsal/ventral neural tube patterning
          cerebral cortex development
          neurogenesis
          neuron differentiation
          embryonic limb morphogenesis
          forebrain development
          positive regulation of proteasomal ubiquitin-dependent protein catabolic process
          endoplasmic reticulum calcium ion homeostasis
          beta-amyloid formation
          segmentation
          intracellular signal transduction
          locomotion
          regulation of phosphorylation
          eye photoreceptor cell development
          amyloid precursor protein catabolic process
          myeloid dendritic cell differentiation
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          positive regulation of catalytic activity
          regulation of protein binding
          positive regulation of MAP kinase activity
          negative regulation of neuron apoptotic process
          skin morphogenesis
          cellular protein metabolic process
          positive regulation of protein kinase activity
          regulation of synaptic plasticity
          thymus development
          neuron development
          skeletal system morphogenesis
          brain morphogenesis
          beta-amyloid metabolic process
          epithelial cell proliferation
          negative regulation of axonogenesis
          positive regulation of coagulation
          T cell receptor signaling pathway
          neuron apoptotic process
          negative regulation of ubiquitin-protein transferase activity
          smooth endoplasmic reticulum calcium ion homeostasis
          protein maturation
          regulation of synaptic transmission, glutamatergic
          canonical Wnt signaling pathway
          regulation of resting membrane potential
          calcium ion transmembrane transport
          negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
          negative regulation of apoptotic signaling pathway
          endopeptidase activity
          aspartic-type endopeptidase activity
          calcium channel activity
          protein binding
          beta-catenin binding
          peptidase activity
          PDZ domain binding
          cadherin binding

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