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          System Message

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          LOADING ...
          See other CASP8 SIRNA Assays ›
          Gene Symbol:
          CASP8
          Gene Name:
          caspase 8
          Gene Aliases:
          ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5
          Chromosome Location:
          Chr.2: 201233443 - 201287711 on Build GRCh38
          UniGene ID:
          Hs.599762
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS141461
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: CASP8
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001080124.1 NP_001073593.1 3 354
          NM_001080125.1 NP_001073594.1 2 497
          NM_001228.4 NP_001219.2 3 422
          NM_033355.3 NP_203519.1 3 328
          NM_033356.3 NP_203520.1 2 259
          NM_033358.3 NP_203522.1 3 422
          NR_111983.1 2 497
          XM_005246885.1 XP_005246942.1 2 317
          XM_005246886.1 XP_005246943.1 2 243
          XM_005246887.1 XP_005246944.1 3 395
          XM_005246888.1 XP_005246945.1 3 337
          XM_005246889.1 XP_005246946.1 2 214
          XM_005246890.3 XP_005246947.1 2 221
          XM_005246891.4 XP_005246948.1 2 461
          XM_005246892.1 XP_005246949.1 2 214
          XM_005246893.2 XP_005246950.1 2 317
          XM_005246894.3 XP_005246951.1 3 392
          XM_005246895.2 XP_005246952.1 2 317
          XM_006712789.1 XP_006712852.1 3 354
          XM_006712790.3 XP_006712853.1 2 233
          XM_006712793.2 XP_006712856.1 3 395
          GenBank mRNA AA312258.1 - 2 240
          AB451282.1 - 1 119
          AB451414.1 - 1 119
          AF009620.1 - 1 119
          AF380342.1 - 2 204
          AF422926.1 - 2 254
          AF422927.1 - 3 342
          AF422928.1 - 3 316
          AF422929.1 - 2 384
          AK310630.1 - 3 395
          AL601594.1 - 2 260
          BC028223.2 - 1 146
          BC068050.1 - 2 209 6421760
          BX395849.2 - 2 208
          CB990598.1 - 3 339
          DA420056.1 - 3 356
          EU168332.1 - 1 119
          EU670044.1 - 1 119
          JN657192.1 - 1 81
          U58143.1 - 1 119
          U60520.1 - 3 375
          X98172.1 - 2 410
          X98173.1 - 2 191
          X98176.1 - 3 308
          X98177.1 - 1 119
          X98178.1 - 1 119

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          proteolysis
          apoptotic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          cellular component disassembly involved in execution phase of apoptosis
          cell surface receptor signaling pathway
          response to cold
          regulation of tumor necrosis factor-mediated signaling pathway
          regulation of necrotic cell death
          natural killer cell activation
          macrophage differentiation
          response to cobalt ion
          response to estradiol
          response to lipopolysaccharide
          response to tumor necrosis factor
          TRIF-dependent toll-like receptor signaling pathway
          TRAIL-activated apoptotic signaling pathway
          suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process
          T cell activation
          B cell activation
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          response to ethanol
          positive regulation of macrophage differentiation
          positive regulation of proteolysis
          response to antibiotic
          protein heterooligomerization
          proteolysis involved in cellular protein catabolic process
          syncytiotrophoblast cell differentiation involved in labyrinthine layer development
          nucleotide-binding oligomerization domain containing signaling pathway
          cellular response to mechanical stimulus
          cellular response to organic cyclic compound
          death-inducing signaling complex assembly
          apoptotic signaling pathway
          extrinsic apoptotic signaling pathway
          execution phase of apoptosis
          activation of cysteine-type endopeptidase activity
          activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
          regulation of extrinsic apoptotic signaling pathway via death domain receptors
          negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
          cysteine-type endopeptidase activity
          death receptor binding
          tumor necrosis factor receptor binding
          protein binding
          peptidase activity
          cysteine-type peptidase activity
          ubiquitin protein ligase binding
          protein complex binding
          death effector domain binding
          identical protein binding
          scaffold protein binding
          cysteine-type endopeptidase activity involved in apoptotic process
          cysteine-type endopeptidase activity involved in apoptotic signaling pathway

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