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          System Message

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          LOADING ...
          See other BMP4 SIRNA Assays ›
          Gene Symbol:
          Bmp4
          Gene Name:
          bone morphogenetic protein 4
          Gene Aliases:
          Bmp-4, Bmp2b, Bmp2b-1, Bmp2b1
          Chromosome Location:
          Chr.14: 46383520 - 46390599 on Build GRCm38
          UniGene ID:
          Mm.6813
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 60437

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Bmp4
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_007554.2 NP_031580.2 4 1341
          GenBank mRNA AK136527.1 - 4 1342
          AK145359.1 - 4 1411
          BC013459.1 - 4 1313 4219098
          BC034053.1 - 3 1162 4192158
          BC052846.1 - 3 1049 30054617
          X56848.1 - 4 1269

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Human: NM_130850, NM_130851, NM_001202, BX161385, BX161438, and others.
          This siRNA also targets the following transcripts in Rat: NM_012827, XM_006251748, XM_006251746, XM_006251749, XM_008770501, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          activation of MAPKK activity
          skeletal system development
          ossification
          angiogenesis
          ovarian follicle development
          blood vessel development
          osteoblast differentiation
          eye development
          metanephros development
          ureteric bud development
          branching involved in ureteric bud morphogenesis
          mesoderm formation
          organ induction
          kidney development
          neural tube closure
          positive regulation of protein phosphorylation
          regulation of endothelial cell proliferation
          positive regulation of endothelial cell proliferation
          vasculature development
          endochondral ossification
          blood vessel endothelial cell proliferation involved in sprouting angiogenesis
          chondrocyte differentiation
          hematopoietic progenitor cell differentiation
          lymphoid progenitor cell differentiation
          renal system process
          BMP signaling pathway involved in heart induction
          secondary heart field specification
          type B pancreatic cell development
          mesenchymal to epithelial transition involved in metanephros morphogenesis
          common-partner SMAD protein phosphorylation
          multicellular organism development
          germ cell development
          mesodermal cell fate determination
          heart development
          positive regulation of cell proliferation
          negative regulation of cell proliferation
          post-embryonic development
          tissue development
          anterior/posterior axis specification
          specification of organ position
          regulation of cell fate commitment
          regulation of gene expression
          positive regulation of calcium ion transport into cytosol
          positive regulation of endothelial cell migration
          positive regulation of gene expression
          negative regulation of gene expression
          positive regulation of pathway-restricted SMAD protein phosphorylation
          positive regulation of cell death
          positive regulation of neuron projection development
          telencephalon development
          dorsal/ventral neural tube patterning
          telencephalon regionalization
          pituitary gland development
          cell differentiation
          erythrocyte differentiation
          monocyte differentiation
          macrophage differentiation
          lung development
          embryonic limb morphogenesis
          positive regulation of bone mineralization
          BMP signaling pathway
          positive regulation of BMP signaling pathway
          forebrain development
          positive regulation of vascular endothelial growth factor receptor signaling pathway
          positive regulation of protein binding
          negative regulation of chondrocyte differentiation
          positive regulation of collagen biosynthetic process
          negative regulation of T cell differentiation in thymus
          negative regulation of immature T cell proliferation in thymus
          protein localization to nucleus
          cellular response to oxidative stress
          embryonic hindlimb morphogenesis
          tendon cell differentiation
          deltoid tuberosity development
          growth
          regulation of protein import into nucleus
          negative regulation of phosphorylation
          odontogenesis of dentin-containing tooth
          odontogenesis
          regulation of odontogenesis of dentin-containing tooth
          embryonic digit morphogenesis
          camera-type eye development
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          steroid hormone mediated signaling pathway
          negative regulation of MAP kinase activity
          cell fate commitment
          regulation of cell differentiation
          positive regulation of cell differentiation
          positive regulation of endothelial cell differentiation
          positive regulation of epidermal cell differentiation
          negative regulation of myoblast differentiation
          positive regulation of neuron differentiation
          positive regulation of osteoblast differentiation
          positive regulation of ossification
          negative regulation of cell cycle
          negative regulation of mitotic nuclear division
          negative regulation of striated muscle tissue development
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          lung alveolus development
          mesodermal cell differentiation
          intermediate mesodermal cell differentiation
          camera-type eye morphogenesis
          embryonic morphogenesis
          anatomical structure formation involved in morphogenesis
          regulation of smooth muscle cell proliferation
          positive regulation of smooth muscle cell proliferation
          neuron fate commitment
          embryonic cranial skeleton morphogenesis
          embryonic skeletal system morphogenesis
          embryonic skeletal system development
          negative regulation of oligodendrocyte differentiation
          smooth muscle tissue development
          branching morphogenesis of an epithelial tube
          positive regulation of epithelial cell proliferation
          negative regulation of epithelial cell proliferation
          positive chemotaxis
          smooth muscle cell differentiation
          regulation of smooth muscle cell differentiation
          cartilage development
          cardiac muscle cell differentiation
          positive regulation of cardiac muscle fiber development
          inner ear receptor cell differentiation
          lens induction in camera-type eye
          embryonic skeletal joint morphogenesis
          bone development
          cranial suture morphogenesis
          positive regulation of SMAD protein import into nucleus
          regulation of pathway-restricted SMAD protein phosphorylation
          SMAD protein signal transduction
          lung morphogenesis
          epithelium development
          bronchus development
          trachea development
          trachea formation
          epithelial tube branching involved in lung morphogenesis
          branching involved in prostate gland morphogenesis
          bud elongation involved in lung branching
          epithelial cell proliferation involved in lung morphogenesis
          bud dilation involved in lung branching
          prostate gland morphogenesis
          negative regulation of cell death
          mammary gland formation
          epithelial-mesenchymal cell signaling
          negative regulation of prostatic bud formation
          regulation of branching involved in prostate gland morphogenesis
          regulation of morphogenesis of a branching structure
          regulation of cartilage development
          positive regulation of cartilage development
          positive regulation of branching involved in lung morphogenesis
          BMP signaling pathway involved in ureter morphogenesis
          BMP signaling pathway involved in renal system segmentation
          pulmonary artery endothelial tube morphogenesis
          negative regulation of thymocyte apoptotic process
          positive regulation of hepatocyte differentiation
          regulation of ERK1 and ERK2 cascade
          positive regulation of ERK1 and ERK2 cascade
          cellular response to growth factor stimulus
          cellular response to dexamethasone stimulus
          BMP signaling pathway involved in nephric duct formation
          renal system development
          negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway
          specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway
          glomerular capillary formation
          negative regulation of glomerular mesangial cell proliferation
          mesenchymal cell differentiation involved in kidney development
          ureter epithelial cell differentiation
          ureter smooth muscle cell differentiation
          negative regulation of mesenchymal cell proliferation involved in ureter development
          metanephric collecting duct development
          positive regulation of kidney development
          positive regulation of branching involved in ureteric bud morphogenesis
          negative regulation of branching involved in ureteric bud morphogenesis
          negative regulation of glomerulus development
          positive regulation of store-operated calcium channel activity
          positive regulation of mesenchymal stem cell proliferation
          negative regulation of metanephric S-shaped body morphogenesis
          negative regulation of metanephric comma-shaped body morphogenesis
          positive regulation of DNA-dependent DNA replication
          negative regulation of cell proliferation involved in heart morphogenesis
          positive regulation of endothelial cell apoptotic process
          mesenchymal cell differentiation involved in renal system development
          cytokine activity
          transforming growth factor beta receptor binding
          protein binding
          growth factor activity
          heparin binding
          chemoattractant activity
          protein homodimerization activity
          BMP receptor binding

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