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Gene Symbol:
TP53
Gene Name:
Gene Aliases:
Species:
Human
Species Specific ID (Flybase ID):
Assay ID Hs00153349_m1
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Availability Inventoried
Catalog # 4331182
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Assay Details

Gene Symbol: TP53
Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
RefSeq NM_000546.5 NP_000537.3 9 - 10 1196 72
NM_001126112.2 NP_001119584.1 9 - 10 1193 72
NM_001126115.1 NP_001119587.1 5 - 6 876 72
NM_001126118.1 NP_001119590.1 8 - 9 1313 72
NM_001276697.1 NP_001263626.1 5 - 6 876 72
NM_001276760.1 NP_001263689.1 9 - 10 1196 72
NM_001276761.1 NP_001263690.1 9 - 10 1193 72
GenBank mRNA AB082923.1 - 9 - 10 1057 72
AF307851.1 - 9 - 10 1129 72
AK223026.1 - 3 - 4 289 72
AK225838.1 - 9 - 10 1134 72
AK297462.1 - 10 - 11 1061 72
AK297927.1 - 10 - 11 1106 72
AK312568.1 - 9 - 10 1138 72
AM076970.1 - 8 - 9 961 72
AY429684.1 - 8 - 9 994 72
BC003596.1 - 9 - 10 1114 3544714 72
BT019622.1 - 8 - 9 994 72
DQ186650.1 - 5 - 6 872 72
DQ191317.1 - 9 - 10 1183 72
DQ263704.1 - 8 - 9 994 72
DQ286964.1 - 9 - 10 1128 72
EF101867.1 - 8 - 9 961 72
FJ207420.1 - 9 - 10 1129 72
JN214348.1 - 8 - 9 1039 72
JN601513.1 - 8 - 9 994 72
JN601514.1 - 8 - 9 994 72
JN601515.1 - 8 - 9 994 72
JN601516.1 - 9 - 10 968 72
JN900492.1 - 8 - 9 1302 72
JQ026207.1 - 8 - 9 984 72
JQ026208.1 - 8 - 9 989 72
JQ026209.1 - 8 - 9 999 72
JQ026210.1 - 8 - 9 989 72
JQ694049.1 - 8 - 9 1017 72
JQ694050.1 - 8 - 9 1017 72
JQ694051.1 - 8 - 9 1017 72
M14694.1 - 9 - 10 1119 72
M14695.1 - 9 - 10 1115 72
X01405.1 - 6 - 7 695 72
X02469.1 - 9 - 10 1129 72
X60011.1 - 8 - 9 994 72
X60012.1 - 8 - 9 994 72
X60013.1 - 8 - 9 994 72
X60014.1 - 8 - 9 994 72
X60015.1 - 8 - 9 994 72
X60016.1 - 8 - 9 994 72
X60017.1 - 8 - 9 994 72
X60018.1 - 8 - 9 994 72
X60019.1 - 8 - 9 994 72
X60020.1 - 8 - 9 994 72

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More Information


Set Membership:

 Ambion siRNA available Amplicon length between 71 and 85 Apoptosis Mammalian Gene Collection Homo sapiens Human Hypoxia Panel Human Tumor Metastasis Panel Human MAP Kinase Pathways Inventoried Human_Hypoxia Human_Map_Kinase Human Tumor Metastasis Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene TP53

Panther Classification:

Molecular Function -

P53-like transcription factor

Gene Ontology Categories:

Function(s) Process(es)

MicroArray Probes:

Affymetrix


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Citations (14)

Conditional gene expression and knockdown using lentivirus vectors encoding shRNA.
Authors
Szulc J, Aebischer P
Journal
Methods Mol Biol - Page No 291 (Tue Jan 01 00:00:00 EST 2008)
Volume (Year)
434 (2008)
Product Usage
-
Effects of model organophosphorous pesticides on DNA damage and proliferation of HepG2 cells.
Authors
Hreljac I, Zajc I, Lah T, Filipic M
Journal
Environ Mol Mutagen - Page No 360 (Sun Jun 01 00:00:00 EDT 2008)
Volume (Year)
49 (2008)
Product Usage
-
Positional expression profiling indicates candidate genes in deletion hotspots of hepatocellular carcinoma.
Authors
Chan KY, Lai PB, Squire JA, Beheshti B, Wong NL, Sy SM, Wong N
Journal
Mod Pathol - Page No 1546 (Fri Dec 01 00:00:00 EST 2006)
Volume (Year)
19 (2006)
Product Usage
-
Mechanisms of p,p'-DDE-induced apoptosis in human peripheral blood mononuclear cells.
Authors
Alegria-Torres JA, Diaz-Barriga F, Gandolfi AJ, Perez-Maldonado IN
Journal
Toxicol In Vitro - Page No 1000 (Tue Sep 01 00:00:00 EDT 2009)
Volume (Year)
23 (2009)
Product Usage
-
Blockade of MGMT expression by O6 benzyl guanine leads to inhibition of pancreatic cancer growth and induction of apoptosis.
Authors
Konduri SD, Ticku J, Bobustuc GC, Sutphin RM, Colon J, Isley B, Bhakat KK, Srivenugopal KS, Baker CH
Journal
Clin Cancer Res - Page No 6087 (Thu Oct 01 00:00:00 EDT 2009)
Volume (Year)
15 (2009)
Product Usage
-
Patterns of microcystin-LR induced alteration of the expression of genes involved in response to DNA damage and apoptosis.
Authors
Zegura B, Zajc I, Lah TT, Filipic M
Journal
Toxicon - Page No 615 (Sat Mar 15 00:00:00 EDT 2008)
Volume (Year)
51 (2008)
Product Usage
-
DNA damage, DNA repair rates and mRNA expression levels of cell cycle genes (TP53, p21CDKN1A, BCL2 and BAX) with respect to occupational exposure to styrene.
Authors
Hanova M, Vodickova L, Vaclavikova R, Smerhovsky Z, Stetina R, Hlavac P, Naccarati A, Slyskova J, Polakova V, Soucek P, Kumar R, Hemminki K, Vodicka P
Journal
Carcinogenesis - Page No (Thu Oct 21 00:00:00 EDT 2010)
Volume (Year)
 (2010)
Product Usage
-
Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors.
Authors
Renaud S, Pugacheva EM, Delgado MD, Braunschweig R, Abdullaev Z, Loukinov D, Benhattar J, Lobanenkov V
Journal
Nucleic Acids Res - Page No 7372 (Mon Jan 01 00:00:00 EST 2007)
Volume (Year)
35 (2007)
Product Usage
-
Differential allelic expression in leukoblast from patients with acute myeloid leukemia suggests genetic regulation of CDA, DCK, NT5C2, NT5C3, and TP53.
Authors
Jordheim LP, Nguyen-Dumont T, Thomas X, Dumontet C, Tavtigian SV
Journal
Drug Metab Dispos - Page No 2419 (Mon Dec 01 00:00:00 EST 2008)
Volume (Year)
36 (2008)
Product Usage
-
Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways.
Authors
Gilmore-Hebert M, Ramabhadran R, Stern DF
Journal
Mol Cancer Res - Page No 1388 (Fri Oct 01 00:00:00 EDT 2010)
Volume (Year)
8 (2010)
Product Usage
-
Bone morphogenetic proteins and receptors are over-expressed in bone-marrow cells of multiple myeloma patients and support myeloma cells by inducing ID genes.
Authors
Grcevic D, Kusec R, Kovacic N, Lukic A, Lukic IK, Ivcevic S, Nemet D, Seiwerth RS, Ostojic SK, Croucher PI, Marusic A
Journal
Leuk Res - Page No 742 (Tue Jun 01 00:00:00 EDT 2010)
Volume (Year)
34 (2010)
Product Usage
-
Regulation of expression of BIK proapoptotic protein in human breast cancer cells: p53-dependent induction of BIK mRNA by fulvestrant and proteasomal degradation of BIK protein.
Authors
Hur J, Bell DW, Dean KL, Coser KR, Hilario PC, Okimoto RA, Tobey EM, Smith SL, Isselbacher KJ, Shioda T
Journal
Cancer Res - Page No 10153 (Sun Oct 15 00:00:00 EDT 2006)
Volume (Year)
66 (2006)
Product Usage
-
Gene expression signature in peripheral blood cells from medical students exposed to chronic psychological stress.
Authors
Kawai T, Morita K, Masuda K, Nishida K, Shikishima M, Ohta M, Saito T, Rokutan K
Journal
Biol Psychol - Page No 147 (Mon Oct 01 00:00:00 EDT 2007)
Volume (Year)
76 (2007)
Product Usage
-
Levetiracetam enhances p53-mediated MGMT inhibition and sensitizes glioblastoma cells to temozolomide.
Authors
Bobustuc GC, Baker CH, Limaye A, Jenkins WD, Pearl G, Avgeropoulos NG, Konduri SD
Journal
Neuro Oncol - Page No 917 (Wed Sep 01 00:00:00 EDT 2010)
Volume (Year)
12 (2010)
Product Usage
-

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