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Gibco™
HEP10, Pooled Human Cryopreserved Hepatocytes
Get the convenience, affordability, and power of a pooled population of hepatocytes in a single vial. HEP10™ Pooled Human HepatocytesRead more
Catalog number HMCS10
Price (USD)
1,342.00
Each
Price (USD)
1,342.00
Each
Get the convenience, affordability, and power of a pooled population of hepatocytes in a single vial. HEP10™ Pooled Human Hepatocytes are a representative population of 10 different donor hepatocytes that have been isolated using our novel proprietary CellStream Isolation Technology™, helping to deliver consistent, predictable results in your drug metabolism studies and other biological assays.
• Pure, highly viable hepatocytes isolated using our CellStream Isolation Technology™
• 10 donor hepatocytes, 5 male and 5 female in each vial
• Verified enzymatic and pathway activity
Each lot is tested for:
• Viability ≥ 75%
• Phase I and II enzyme activities
• Transporter suspension uptake
CellStream™ Isolation Technology
HEP10™ Pooled Human Hepatocytes are made using our novel proprietary CellStream Isolation Technology™. This process eliminates the disadvantages of density gradient fractionation prior to cryopreservation of the pool. Instead, we gently isolate and purify the pre-screened, high-viability, and metabolically-active hepatocytes from other cells and debris. The result is a remarkably pure pooled hepatocyte preparation with high viability for use in drug metabolism studies and other biological assays.
10 Donors in One Vial
Each vial of HEP10™ Pooled Human Hepatocytes contains hepatocytes from ten individual donors, 5 female and 5 male donors. Custom HEP10 lots can also be prepared from our broad array of high-quality, single-donor cells. Large lots are also available for extensive studies.
Verified Activity
Each pool is characterized for CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A4⁄5, FMO activity, and NTCP, OATP1B3, and OATP transporter pathways.
Ready for Your Drug Metabolism Experiments
HEP10™ Pooled Human Hepatocytes are useful in a wide variety of applications, including intrinsic clearance, transport, toxicology, biochemistry and cell biology studies.,
Note:
These products require shipment in LN2 vapor dewars therefore additional fees may apply.
• Pure, highly viable hepatocytes isolated using our CellStream Isolation Technology™
• 10 donor hepatocytes, 5 male and 5 female in each vial
• Verified enzymatic and pathway activity
Each lot is tested for:
• Viability ≥ 75%
• Phase I and II enzyme activities
• Transporter suspension uptake
CellStream™ Isolation Technology
HEP10™ Pooled Human Hepatocytes are made using our novel proprietary CellStream Isolation Technology™. This process eliminates the disadvantages of density gradient fractionation prior to cryopreservation of the pool. Instead, we gently isolate and purify the pre-screened, high-viability, and metabolically-active hepatocytes from other cells and debris. The result is a remarkably pure pooled hepatocyte preparation with high viability for use in drug metabolism studies and other biological assays.
10 Donors in One Vial
Each vial of HEP10™ Pooled Human Hepatocytes contains hepatocytes from ten individual donors, 5 female and 5 male donors. Custom HEP10 lots can also be prepared from our broad array of high-quality, single-donor cells. Large lots are also available for extensive studies.
Verified Activity
Each pool is characterized for CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A4⁄5, FMO activity, and NTCP, OATP1B3, and OATP transporter pathways.
Ready for Your Drug Metabolism Experiments
HEP10™ Pooled Human Hepatocytes are useful in a wide variety of applications, including intrinsic clearance, transport, toxicology, biochemistry and cell biology studies.,
Note:
These products require shipment in LN2 vapor dewars therefore additional fees may apply.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Cell Passage NumberPassage 0
Cell TypeHepatocytes
Culture TypeSuspension Cell Culture
FormCryopreserved
GenderUnisex
SpeciesHuman
Donor SourcePooled
FormatTube
No. of Cells4-8 x 106
Product LineGibco™
Product TypeHepatocytes
Quantity1.5 mL
Tested ForPhase I and II Enzyme Activity, Transporter Suspension Uptake, Viability ≥75%
Unit SizeEach
Contents & Storage
Store in a cryostorage dewar or -135°C freezer.