GeneChip™ miRNA 4.1 Array Plate

Name: GeneChip™ miRNA 4.1 Array Plate
SKU: 902410

Many diseases, including cancer, are frequently described as diseases of disordered gene expression. It is estimated that more than 30%Read more

Change view

Catalog Number	Number of Arrays
902410	96 arrays
902408TS	16 arrays
902409	24 arrays

3 Options

Catalog number 902410

Price (USD)

Number of Arrays:

96 arrays

Many diseases, including cancer, are frequently described as diseases of disordered gene expression. It is estimated that more than 30% of protein translation of coding genes is regulated by miRNA. There is also a large amount of growing evidence suggesting miRNA interacts with long non-coding RNA in the signaling networks that regulate alternative splicing events, which impacts cellular processes such as apoptosis, proliferation, and differentiation. All of which have shown to be causative elements in diseases such as cancer.

Measuring the changes in these critical nodes of regulation is extremely important for deciphering the biological context of differentially expressed genes. This array design is a powerful tool for studying the role of small non-coding RNAs and their involvement in a broad spectrum of developmental and physiological mechanisms.

To keep pace with the discovery of new and novel miRNA, we are pleased to offer the miRNA 4.1 96-Array Plates and Trays in our catalog of miRNA arrays. This product offers updated content with the same high performance as the previous generation array.

miRNA 4.1 Array Plates and Trays help bring you closer to biology with:
• Comprehensive coverage – Designed to interrogate all mature miRNA sequences in miRBase Release 20
• Easily correlate miRNA results – Analysis files contain host gene ID, predicted and validated miRNA target genes, and clustered miRNA information
• Easy analysis – Analyze human, mouse, rat, or every miRNA for all species using the same array
• Low sample input – Requires as little as 130 ng total RNA
• Simple, fast, and free analysis solution – Coupled with Expression Console™ Software and Transcriptome Analysis Console (TAC) Software, researchers have a complete solution from data to decision-making in minutes

Related Links
GeneTitan™ Wash Buffers A and B Module
B2 Control Oligo (3nM)
Genetitan™ miRNA Array Holding Buffer
FlashTag™ Biotin HSR RNA Labeling Kits
FlashTag™ Biotin HSR RNA Labeling Kits
GeneTitan™ Hybridization Module for miRNA Plates
GeneChip™ Hybridization Control Kit

For Research Use Only. Not for use in diagnostic procedures.

Specifications

TypemiRNA 4.1 Array Plate

ArraymiRNA Profiling

Number of Arrays96 arrays

Format96-array Plate, Trays

SpeciesAll Organisms, Human, Mouse, Rat

Product LineGeneChip™

Unit SizeEach

Frequently asked questions (FAQs)

Is the hybridization mix for cartridges the same as the hybridization mix for PEG arrays (array plates)?

The hybridization mix for PEG arrays is different from the hybridization mix for cartridges. The concentrations of the hybridization mix are different and in addition, DMSO is not added into the hybridization mix for PEG arrays because it can affect the glue that holds the PEG to the plate.

Where can I find the species information for your GeneChip miRNA arrays?

The species information can be found in the annotation file of the miRNA array of interest.
Please complete the following steps:
- Go to www.thermofisher.com and go to the product page of the array of interest.
- Scroll down to support files.
- Download the annotation files for the miRNA array of interest, and open in excel.
- In the file, there will be a column, species scientific name. This column will have all the species present on the array.

Find additional tips, troubleshooting help, and resources within our Microarray Analysis Support Center.

How are sno/sca and hairpin probe sets selected and how does that impact my signal summarization?

Probes for snoRNA, scaRNA, and hairpins are selected to maximize probe response to target concentration in the sample while minimizing cross-hybridization to other potential targets in the sample. In order to minimize cross-hybridization, potential targets are inferred from the landscape of known sequences from the input dataset and used in a filtering process called pruning which penalizes probe candidates that may cross-hybridize to unwanted targets. As the landscape of known sequences improves, we can improve our pruning set to avoid probe candidates previously thought to be unique. An improved pruning set will reduce the chances a probe will cross-hybridize to unwanted target, improving the probe set representation of the intended target. As a result of the improved probe selection, few probe sets are required to represent the same number of sequences.

Find additional tips, troubleshooting help, and resources within our Microarray Analysis Support Center.

Can I combine the CEL files from GeneChip miRNA Arrays, miRNA Array Strips, and miRNA Array Plates into the same experiment?

No, the CEL files from GeneChip miRNA Array, Thermo Fisher Scientific miRNA Array Strip, and miRNA Array Plates are not compatible.

Find additional tips, troubleshooting help, and resources within our Microarray Analysis Support Center.

What is the difference between GeneChip miRNA Array, miRNA Array Strip, and miRNA Array Plate?

The only difference is the form factor of the array. The arrays have the exact same design and contain the same number of probes and probe sets.

Find additional tips, troubleshooting help, and resources within our Microarray Analysis Support Center.

View all GeneChip™ miRNA 4.1 Array Plate FAQs