PAC-dA Phosphoramidite, standard grade, serum vial bottle
PAC-dA Phosphoramidite, standard grade, serum vial bottle
Thermo Scientific™

PAC-dA Phosphoramidite, standard grade, serum vial bottle

PAC-dA CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxyadenosine (dA) with Phenoxyacetyl (PAC) base protection, for useRead more
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Catalog number 27-1723-04
Price (USD)
71.75
Each
Add to cart
Price (USD)
71.75
Each
Add to cart

PAC-dA CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxyadenosine (dA) with Phenoxyacetyl (PAC) base protection, for use in oligonucleotide synthesis. The UltraMILD monomers - phenoxyacetyl (PAC)-dA, acetyl (Ac)-dC, and iso-propyl-phenoxyacetyl (iPr-PAC)-dG - were developed to alleviate the problem of modifiers and labels not withstanding prolonged exposure to strongly alkaline deprotection conditions. Cleavage and deprotection can be achieved in 4 hours at room temperature with 0.05M potassium carbonate in methanol. The 'Standard Grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 20 mL Amber bottle with a Serum Vial neck style, which is compatible with most ABI Systems|AKTA Systems of oligonucleotide synthesizers.

Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C48H54N7O8P
• Base—dA
• Base Protection—PAC
• Formula weight—887.96 g/mol
• CAS number—110543-74-3
• HPLC Purity—≥98.0%
31P NMR Purity—≥98.0%

For Research Use Only. Not for use in diagnostic procedures.
Specifications
For Use With (Equipment)AKTA Synthesizers, Applied Biosystems Synthesizers
Product TypePAC-dA CEP
Nucleoside TypeDeoxyadenosine (dA)
Reagent FeaturesFast deprotection
Shipping ConditionRoom Temperature
Purity98%
Quantity1 g
Reagent TypePhosphoramidite
GradeStandard
Nucleic Acid TypeDNA
FormPowder
Unit SizeEach
Contents & Storage
Store in freezer (at or below -20°C).