Cover story

TUNEL Vision—Detect DNA fragmentation with Click-iT TUNEL assays

For a reliable and reproducible TUNEL imaging assay, it is vital not only that the modified nucleotide is an acceptable substrate for TdT, but also that the detection method is sensitive and avoids any additional loss of cells from the sample. The Click-iT TUNEL Imaging Assays meet both of these criteria.

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Also in this issue

New Technologies

  • Assess hERG channel blocks without radioactivity—The Predictor hERG Fluorescence Polarization Assay Kit
  • Characterization of type II kinase inhibitors and nonactivated kinases—The LanthaScreen Eu Kinase Binding Assay
  • High-throughput chloride channel screening—Introducting the newest member of the Premo family: Premo Halide Sensor
  • Fluorescence technologies for high-content imaging and analysis—Cell health and toxicity assays
  • Novel solid-phase antibody labeling—Take advantage of the speed, efficiency, and convenience of APEX Antibody Labeling Kits
  • Automated cell counting at your fingertips—The Countess Automated Cell Counter
     

Practical Applications

  • Dynamic signaling by integrins—Protein phosphorylation and activation of networks
  • Targeting cardiovascular disease and Alzheimer's disease—Beyond regulating cholesterol levels, new drug targets emerge from lipid research
  • Modeling mammary cell function in three dimensions—BacMam-medicated transduction and 3D culture of primary mammary cells
  • Hassle-free western blots—WesternDot 625 Western Blot Kits
     

Departments

  • Journal Highlight—Staining DNA without altering its structure
  • On the Web—Easy access to Molecular Probes products
  • Just Released—Highlighting our newest cellular analysis products and technologies
  • Endnote—Recently published: A look at how your fellow researchers are using our products

仅供科研使用，不可用于诊断目的。