Invitrogen

hnRNP DL Polyclonal Antibody

hnRNP DL Antibody in Immunocytochemistry (ICC/IF)

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hnRNP DL Antibody (PA5-78306) in ICC/IF

Immunofluorescent analysis of HNRPDL in HeLa cells. Samples were treated with 4% paraformaldehyde at RT for 15 min and incubated with HNRPDL polyclonal antibody (Product # PA5-78306) using a dilution of 1:500, followed by Hoechst.

hnRNP DL Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

PA5-78306

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000

Immunocytochemistry (ICC/IF)

1:100-1:1,000

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human HNRPDL. The exact sequence is proprietary.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

AB_2735914

Product Specific Information

Positive Control: 293T, A431, HeLa, HepG2, A549, H1299, HCT116

Predicted Reactivity: Chicken (93%), Rhesus Monkey (100%), Bovine (100%)

Target Information

hnRNP DL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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