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PA1-4227 detects the Eukaryotic Translation Initiation Factor 5A2 (eIF5A2) in human, mouse, and rat samples.
PA1-4227 has been successfully used in Western blot and immunohistochemical procedures.
The PA1-4227 immunogen is a synthetic peptide corresponding to the C-terminal residues 108-122 of human EIF5A2.
mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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