Invitrogen

beta Amyloid (1-42) Polyclonal Antibody

beta Amyloid (1-42) Antibody in Western Blot (WB)

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beta Amyloid (1-42) Antibody (PA3-16761) in WB

Detection of Abeta 42 on 5 ng of peptide per lane using PA3-16761 (lot A). Lane 1: Abeta-40, lane 2: Abeta-42, lane 3: Abeta-40 and -42 mix. Band appears at approximately 6 kDa.

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Product Details

PA3-16761

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 1 publication 1 publication

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunoprecipitation (IP)

1:100

Product Specifications

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Whole Abeta 42 peptide.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

This antibody is not recommended for ELISA applications.

Target Information

Beta amyloid is a 40-43 amino acid peptide cleaved from amyloid precursor protein by a protease, gamma-secretase. Beta Amyloid (1-40) (Amyloid beta 40 or Abeta 40) together with beta Amyloid (1-42) (Amyloid beta 42 or Abeta 42) are two major C-terminal variants of the amyloid beta protein, constituting the majority of amyloid beta proteins. Both the Amyloid beta 40 and Amyloid beta 42 alloforms are major components of the extracellular plaques found in Alzheimer's disease brain tissue.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

TrkB activation by 7, 8-dihydroxyflavone increases synapse AMPA subunits and ameliorates spatial memory deficits in a mouse model of Alzheimer's disease.

Journal of neurochemistry

Gao L,Tian M,Zhao HY,Xu QQ,Huang YM,Si QC,Tian Q,Wu QM,Hu XM,Sun LB,McClintock SM,Zeng Y

PA3-16761 was used in western blot to determine how an increase in synapse AMPA subuit and amelioration of spatial memory deficits occurs by TrkB activation by 7,8-dihydroxyflavone in a mouse model of Alzheimer's disease

Mon Feb 01 00:00:00 UTC 2016

Early temporal short-term memory deficits in double transgenic APP/PS1 mice.

Neurobiology of aging

Lagadec S,Rotureau L,Hémar A,Macrez N,Delcasso S,Jeantet Y,Cho YH

PA3-16761 was used in immunohistochemistry to investigate the changes of specific memory function in APP/PS1 transgenic mice

Sun Jan 01 00:00:00 UTC 2012

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