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Invitrogen
alpha Actinin 1 Polyclonal Antibody
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FIGURE: 1 / 1
alpha Actinin 1 Antibody (PA1-28036) in GS
BioMed research international 2014 -
Figure 2 Identification of T. vaginalis TvACTN3 by 1-D gel electrophoresis and mass spectrometry. (a) UV Cross-linking assay of 32 P-labeled IRE-fer and IRE-tvcp4 transcripts and T. vaginalis cytoplasmic extracts grown under iron-depleted conditions (Tv-L) (lanes 2 and 7, resp.). The specificity of the interaction was demonstrated by treatment with proteinase K (10 mu g, Promega) (lanes 3 and 8) and RNases ... View More
Product Details
PA1-28036
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length native alpha actinin purified from chicken gizzard.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_1956052
Product Specific Information
Recommended positive controls: chicken fibroblast, chicken gizzard.
Expected to cross-react with a wide range of tther species due to sequence homology.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Alpha Actinin 1 belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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