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Invitrogen
ZNF83 Polyclonal Antibody
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Product Details
PA5-30741
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human ZNF83. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2548215
Product Specific Information
Recommended positive controls: NT2D1, IMR32.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The ZNF83 gene encodes a zinc-finger protein belonging to a large family of transcription factors that play essential roles in regulating gene expression by interacting with DNA. Located on chromosome 3, ZNF83 is particularly notable for its recurrent mutations in cancer. For instance, the p.E293V missense mutation in ZNF83 has been frequently observed in bladder cancer patients, accounting for 18% of cases, and is associated with poor prognosis. This mutation disrupts the gene's tumor suppressor function, promoting increased tumor growth. Due to its significant role in tumorigenesis, ZNF83 is actively studied in cancer research as a potential biomarker and therapeutic target.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Zinc finger protein 816B; Zinc finger protein 83; Zinc finger protein HPF1
Gene Aliases: HPF1; ZNF816B; ZNF83
UniProt ID: (Human) P51522
Entrez Gene ID: (Human) 55769
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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