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PA1-31354 detects ZNF261 from human samples.
PA1-31354 has been successfully used in Western blot applications.
The PA1-31354 immunogen is: The epitope recognized by this antibody maps to a region between residues 250 and 300 (K PEVVDSTESI PVSDEDSDAM VDDPNDEDFV PFRPRRSPRM SLRSSVSQRA) of Human ZNF261 using the numbering given in entry NP_005087.1 (GeneID 9203).
This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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