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Immunogen sequence: KDEEPTVKQE IEEIEEEVEP QGVIVTRIKS EIDQDPMGRE TFELVGRLDK QRGIFLWEIP RESLTQEQRM FRENTNIIRK RPN
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 80%.
Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Zinc finger protein 189
Gene Aliases: ZNF189
UniProt ID: (Human) O75820
Entrez Gene ID: (Human) 7743
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