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Immunogen sequence: SESGDRLDPTA VNILQQIIEL GAETHDATAL ASVVAMAPGT VTVVKQVTEE EPSSNHTVMI QETVQQASVE LAEQHHLVVS SDDVEGIETV TVYTQGGEAS EFIVYVQE
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 94%.
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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