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Invitrogen
XTP4 Polyclonal Antibody
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FIGURE: 1 / 1
XTP4 Antibody (PA1-31180) in WB
Cancers 2020 -
Figure 1 Co-immunoprecipitation of HMGB2 and MIEN1 or NOP53 ( A ) in SKOV-3 cells ( B ) in PEO1 cells. Proteins extracted from cells (Input) were immunoprecipitated with HMGB2 antibodies (IP anti HMMGB2) or IgG (IP anti IgG) and the Western blot were incubated with HMGB2, MIEN1 and NOP53 antibodies.
Product Details
PA1-31180
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide SNGETLEKITNSRPPC, corresponding to C terminal amino acids 97-112 of Human XTP4.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_1961397
Product Specific Information
PA1-31180 detects XTP4 from human samples.
PA1-31180 has been successfully used in Western blot applications.
The PA1-31180 immunogen is: Synthetic peptide: SNGETLEKITNSRPPC, corresponding to C terminal amino acids 97-112 of Human XTP4.
Target Information
During the past decade, the role of the ERBB2(neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established. The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies. The C35 gene is located on chromosome 17q12, 505nucleotides from the 3' end of the ERBB2oncogene, the antigenic target for trastuzumab(Herceptin) therapy. The chromosomal arrangement of the genes encoding C35 andERBB2 is tail to tail. The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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