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Invitrogen
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Immunogen sequence: GLLVWQQEEPS EFDLAYADFL ALDISM
Highest antigen sequence identity to the following orthologs - mouse 74%, rat 74%.
Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Has no effect on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it does not act prior the onset of apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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