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Invitrogen
WDR65 Polyclonal Antibody
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Product Details
PA5-31657
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human WDR65. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2549130
Product Specific Information
Recommended positive controls: 293T, A431, Jurkat.
Predicted reactivity: Mouse (83%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The WDR65 gene, which stands for WD Repeat Domain 65, encodes a protein characterized by the presence of WD repeat domains that facilitate protein-protein interactions. This gene is implicated in the assembly of a subset of inner arm dyneins, critical for ciliary motility and axonemal structure. Mutations in WDR65 have been associated with diseases such as Van der Woude syndrome (VWS) and related craniofacial disorders, highlighting its role in developmental processes. Specifically, a missense mutation in WDR65 was identified as a potential cause of VWS, suggesting that WDR65 is a target for regulatory factors like IRF6.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cilia- and flagella-associated protein 57; WD repeat-containing protein 65
Gene Aliases: CFAP57; VWS2; WDR65
UniProt ID: (Human) Q96MR6
Entrez Gene ID: (Human) 149465
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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