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Invitrogen
WBSCR16 Polyclonal Antibody
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Product Details
PA5-65705
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human WBSCR16
Conjugate
Form
Liquid
Concentration
Lot-Specific
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2664405
Product Specific Information
Immunogen sequence: TLLSSKTADVT KVWGMGLNKD SQLGFHRSRK DKTRGYEYVL EPSPVSLPLD RPQETRVLQV SCGRAHSLVL TDREGVFSMG NNSYGQCGRK VVEN
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 94%.
Target Information
Guanine nucleotide exchange factor (GEF) for mitochondrial dynamin-related GTPase OPA1. Activates OPA1, by exchanging bound GDP for free GTP, and drives OPA1 and MFN1-dependent mitochondrial fusion. Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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