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Invitrogen
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Immunogen sequence: EGQYYLQICA LLKCQTTDLE TCGEPVGSAF TKFEDFSLSG TFGTRYVFPQ IILSGSQLAP ERHYEISRDG RLRSRSGAPL PVLVMALYGR VFEKDPPRLG QGSGKFQ
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 88%.
The vanin family is a novel group of ectoenzymes that function in tissue repair and plays a role in oxidative-stress response. As both secreted and membrane proteins, the vanin family members have been implicated as therapeutic targets in inflammatory disease. VNN3 (vascular non-inflammatory molecule 3), also known as Vanin3, is a 501 amino acid GPI-anchored amidohydrolase that is widely expressed and is found at highest levels in blood and liver. Induced by Th17 / Th1 type cytokines, VNN3 converts pantetheine into pantothenic acid. Containing one CN hydrolase domain, VNN3 is encoded by a gene that maps to human chromosome 6q23.2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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