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PA1-10887 detects TERE1 in human samples. Both mouse and rat TERE1 proteins are 85% homologous to the human TERE1 protein.
PA1-10887 has been successfully used in Western blot procedures, where a band of approximately 37 kDa is detected.
PA1-10887 immunogen is a synthetic peptide corresponding to amino acids 32-45 of human TERE1.
A novel gene designated TERE1, has a significant effect on the growth regulation in bladder cancer. The TERE1 gene maps to a chromosome locus that has been identified by loss of heterozygosity studies as a site of a putative tumor suppressor gene or genes for multiple tumor types including prostate carcinoma. Data suggest that TERE1 may be significant in prostate cancer growth regulation and the down regulation or absence of TERE1 may be an important component of the phenotype of advanced disease. Data also suggest a potential role for this gene product in the progression of bladder cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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