Product References
Cell Competition Shapes Metastatic Latency and Relapse.
Cancer discovery
Kim K,Huang H,Parida PK,He L,Marquez-Palencia M,Reese TC,Kapur P,Brugarolas J,Brekken RA,Malladi S
R10367 was used in Immunocytochemistry to demonstrate cell competition within the primary tumor results in displacement of latent metastatic cells, and the impact of altering cell competition dynamics on metastatic incidence that may guide strategies to limit metastatic recurrences.
Mon Jan 09 00:00:00 UTC 2023
Adaptable, turn-on maturation (ATOM) fluorescent biosensors for multiplexed detection in cells.
Nature methods
Sekhon H,Ha JH,Presti MF,Procopio SB,Jarvis AR,Mirsky PO,John AM,Loh SN
R10367 was used in Immunocytochemistry to created a family of adaptable, turn-on maturation (ATOM) biosensors consisting of a monobody (circularly permuted at one of two positions) or a nanobody (circularly permuted at one of three positions) inserted into a fluorescent protein at one of three surface loops.
Fri Dec 01 00:00:00 UTC 2023
PLK1-mediated phosphorylation of β-catenin enhances its stability and transcriptional activity for extracellular matrix remodeling in metastatic NSCLC.
Theranostics
Kim DE,Shin SB,Kim CH,Kim YB,Oh HJ,Yim H
R10367 was used in Western Blotting to provide evidence for the critical role of the PLK1/β-catenin/AP-1 axis in metastatic NSCLC, implying that β-catenin and PLK1 may serve as a molecular target and prognostic indicator of the therapeutic response in metastatic NSCLC patients.
Fri Feb 17 00:00:00 UTC 2023
A phosphate-sensing organelle regulates phosphate and tissue homeostasis.
Nature
Xu C,Xu J,Tang HW,Ericsson M,Weng JH,DiRusso J,Hu Y,Ma W,Asara JM,Perrimon N
R10367 was used in Immunohistochemistry to identify connector of kinase to AP-1 (Cka), a component of the STRIPAK complex and JNK signalling3, as the mediator of PXo knockdown- or Pi starvation-induced hyperproliferation.
Mon May 01 00:00:00 UTC 2023
4-Phenylbutyrate restores localization and membrane repair to human dysferlin mutations.
iScience
Tominaga K,Tominaga N,Williams EO,Rufibach L,Schöwel V,Spuler S,Viswanathan M,Guarente LP
R10367 was used in Western Blot to describe a cell-based assay in which human DYSF proteins bearing missense mutations are quantitatively assayed for membrane localization by flow cytometry and identified 64 localization-defective DYSF mutations.
Fri Jan 21 00:00:00 UTC 2022
Drosophila Unfolded Protein Response (UPR) Assays In Vitro and In Vivo.
Methods in molecular biology (Clifton, N.J.)
Katow H,Vasudevan D,Ryoo HD
R10367 was used in Western Blot to detect UPR in Drosophila melanogaster.
Tue Mar 29 00:00:00 UTC 2022
Generation of an Ihh-mKate2-Dre knock-in mouse line.
Genesis (New York, N.Y. : 2000)
Li R,Cai Y,Lin H,Dong L,Tang M,Lang Y,Qi Y,Peng Y,Zhou B,Yang G,Teng Y,Yang X
R10367 was used in Immunohistochemistry to examine the precise expression profile of Ihh and trace Ihh-expressing cells and their progeny.
Fri Jul 01 00:00:00 UTC 2022
DMP8 and 9 regulate HAP2/GCS1 trafficking for the timely acquisition of sperm fusion competence.
Proceedings of the National Academy of Sciences of the United States of America
Wang W,Xiong H,Zhao P,Peng X,Sun MX
R10367 was used in Immunocytochemistry to suggest that seed plants evolved a DMP8/9-dependent fusogen translocation process to achieve timely acquisition of sperm fusion competence in response to egg cell-derived signals, revealing a previously unknown critical step for successful fertilization.
Tue Nov 08 00:00:00 UTC 2022
Systematic In Vivo Characterization of Fluorescent Protein Maturation in Budding Yeast.
ACS synthetic biology
Guerra P,Vuillemenot LA,Rae B,Ladyhina V,Milias-Argeitis A
R10367 was used in Western Blot to study in vivo maturation for 12 fluorescent proteins in budding yeast.
Fri Mar 18 00:00:00 UTC 2022
Two-step regulation of centromere distribution by condensin II and the nuclear envelope proteins.
Nature plants
Sakamoto T,Sakamoto Y,Grob S,Slane D,Yamashita T,Ito N,Oko Y,Sugiyama T,Higaki T,Hasezawa S,Tanaka M,Matsui A,Seki M,Suzuki T,Grossniklaus U,Matsunaga S
R10367 was used in Immunoprecipitation to demonstrate the importance of centromere distribution for the maintenance of genome integrity through the cytogenic and molecular analysis of mutants defective in centromere distribution.
Mon Aug 01 00:00:00 UTC 2022
Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer.
Molecular cell
Einstein JM,Perelis M,Chaim IA,Meena JK,Nussbacher JK,Tankka AT,Yee BA,Li H,Madrigal AA,Neill NJ,Shankar A,Tyagi S,Westbrook TF,Yeo GW
R10367 was used in Western Blot to identify RNA-binding protein candidates involved in MYC-driven oncogenic pathways in cancer.
Thu Aug 05 00:00:00 UTC 2021
Convergence of mammalian RQC and C-end rule proteolytic pathways via alanine tailing.
Molecular cell
Thrun A,Garzia A,Kigoshi-Tansho Y,Patil PR,Umbaugh CS,Dallinger T,Liu J,Kreger S,Patrizi A,Cox GA,Tuschl T,Joazeiro CAP
R10367 was used in Immunocytochemistry-immunoflourescence to study RQC-mediated proteolytic targeting of ribosome stalling products in mammalian cells.
Thu May 20 00:00:00 UTC 2021
Molecular classification of zebrafish retinal ganglion cells links genes to cell types to behavior.
Neuron
Kölsch Y,Hahn J,Sappington A,Stemmer M,Fernandes AM,Helmbrecht TO,Lele S,Butrus S,Laurell E,Arnold-Ammer I,Shekhar K,Sanes JR,Baier H
R10367 was used in Immunohistochemistry to establish a framework for systematically studying the functional architecture of the visual system.
Wed Feb 17 00:00:00 UTC 2021
A Disynaptic Circuit in the Globus Pallidus Controls Locomotion Inhibition.
Current biology : CB
Aristieta A,Barresi M,Azizpour Lindi S,Barrière G,Courtand G,de la Crompe B,Guilhemsang L,Gauthier S,Fioramonti S,Baufreton J,Mallet NP
R10367 was used in Immunohistochemistry to elucidate the circuit mechanisms and subsequent effects of the pathways involving prototypic and arkypallidal neurons.
Mon Feb 22 00:00:00 UTC 2021
Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits.
PLoS biology
Arveseth CD,Happ JT,Hedeen DS,Zhu JF,Capener JL,Klatt Shaw D,Deshpande I,Liang J,Xu J,Stubben SL,Nelson IB,Walker MF,Kawakami K,Inoue A,Krogan NJ,Grunwald DJ,Hüttenhain R,Manglik A,Myers BR
R10367 was used in Western Blotting to demonstrate a mechanism directly linking Hh signal transduction at the membrane to GLI transcription in the nucleus.
Thu Apr 01 00:00:00 UTC 2021
Opponent vesicular transporters regulate the strength of glutamatergic neurotransmission in a C. elegans sensory circuit.
Nature communications
Choi JH,Horowitz LB,Ringstad N
R10367 was used in Immunomicroscopy to indicate that in vivo the strength of glutamatergic synapses is controlled by regulation of neurotransmitter packaging into synaptic vesicles via functional coupling of VGLUT and VST-1.
Wed Nov 03 00:00:00 UTC 2021
Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity.
Nature metabolism
Porniece Kumar M,Cremer AL,Klemm P,Steuernagel L,Sundaram S,Jais A,Hausen AC,Tao J,Secher A,Pedersen TÅ,Schwaninger M,Wunderlich FT,Lowell BB,Backes H,Brüning JC
R10367 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to reveal a critical role of tanycyte insulin receptors in gating feeding-state-dependent regulation of AgRP neurons and systemic insulin sensitivity, and show that insulin resistance in tanycytes contributes to the pleiotropic manifestations of obesity-associated insulin resistance.
Wed Dec 01 00:00:00 UTC 2021
A two-track model for the spatiotemporal coordination of bacterial septal cell wall synthesis revealed by single-molecule imaging of FtsW.
Nature microbiology
Yang X,McQuillen R,Lyu Z,Phillips-Mason P,De La Cruz A,McCausland JW,Liang H,DeMeester KE,Santiago CC,Grimes CL,de Boer P,Xiao J
R10367 was used in Western Blot to suggest a two-track model, in which inactive sPG synthases follow the 'Z-track' to be distributed along the septum and FtsN promotes their release from the Z-track to become active in sPG synthesis on the slow 'sPG-track'.
Sat May 01 00:00:00 UTC 2021
A live imaging system to analyze spatiotemporal dynamics of RNA polymerase II modification in Arabidopsis thaliana.
Communications biology
Shibuta MK,Sakamoto T,Yamaoka T,Yoshikawa M,Kasamatsu S,Yagi N,Fujimoto S,Suzuki T,Uchino S,Sato Y,Kimura H,Matsunaga S
R10367 was used in Western Blotting to develop a genetically encoded fluorescent probe for RNA polymerase II modification Ser2P using a mintbody in Arabidopsis thaliana for live-cell imaging.
Fri May 14 00:00:00 UTC 2021
Local oncolytic adenovirotherapy produces an abscopal effect via tumor-derived extracellular vesicles.
Molecular therapy : the journal of the American Society of Gene Therapy
Kakiuchi Y,Kuroda S,Kanaya N,Kumon K,Tsumura T,Hashimoto M,Yagi C,Sugimoto R,Hamada Y,Kikuchi S,Nishizaki M,Kagawa S,Tazawa H,Urata Y,Fujiwara T
R10367 was used in Immunohistochemistry (Paraffin) to develop a telomerase-specific oncolytic adenovirus, Telomelysin (OBP-301), and occasionally observed therapeutic effects on distal tumors after local treatment in immunodeficient mice.
Wed Oct 06 00:00:00 UTC 2021
Functional Analysis of the GPI Transamidase Complex by Screening for Amino Acid Mutations in Each Subunit.
Molecules (Basel, Switzerland)
Liu SS,Jin F,Liu YS,Murakami Y,Sugita Y,Kato T,Gao XD,Kinoshita T,Hattori M,Fujita M
R10367 was used in Western Blotting to provide guidance for the structural and functional analysis of GPI-TA.
Wed Sep 08 00:00:00 UTC 2021
m6A-binding YTHDF proteins promote stress granule formation.
Nature chemical biology
Fu Y,Zhuang X
R10367 was used in Immunocytochemistry-immunoflourescence to demonstrate m6A-binding YTHDF proteins regulate stress granule formation under stress conditions.
Tue Sep 01 00:00:00 UTC 2020
Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
The EMBO journal
Khosravi B,LaClair KD,Riemenschneider H,Zhou Q,Frottin F,Mareljic N,Czuppa M,Farny D,Hartmann H,Michaelsen M,Arzberger T,Hartl FU,Hipp MS,Edbauer D
R10367 was used in Immunocytochemistry-immunoflourescence to demonstrate that poly-GA inhibits the proteasome and promotes TDP-43 mislocalization and aggregation.
Wed Apr 15 00:00:00 UTC 2020
UPF2 leads to degradation of dendritically targeted mRNAs to regulate synaptic plasticity and cognitive function.
Molecular psychiatry
Notaras M,Allen M,Longo F,Volk N,Toth M,Li Jeon N,Klann E,Colak D
R10367 was used in Immunohistochemistry to establish that UPF2 regulates synaptic plasticity, cognition, and local protein synthesis in dendrites, providing fundamental insight into the neuron-specific function of NMD within the brain.
Tue Dec 01 00:00:00 UTC 2020
Disruption of EGF Feedback by Intestinal Tumors and Neighboring Cells in Drosophila.
Current biology : CB
Ngo S,Liang J,Su YH,O'Brien LE
R10367 was used in Immunohistochemistry to demonstrate that Drosophila APC-/- tumors trigger widespread Rho expression in non-apoptotic cells, resulting in chronic EGF signaling.
Mon Apr 20 00:00:00 UTC 2020
Subcellular Localization of Rice Acyl-CoA-Binding Proteins ACBP4 and ACBP5 Supports Their Non-redundant Roles in Lipid Metabolism.
Frontiers in plant science
Liao P,Leung KP,Lung SC,Panthapulakkal Narayanan S,Jiang L,Chye ML
R10367 was used in Western Blot to suggest that OsACBP4 is likely involved in the intracellular shuttling of acyl-CoA esters and/or other lipids between the plasma membrane and the ER, while OsACBP5 appears to participate in the extracellular transport of acyl-CoA esters and/or other lipids, suggesting that they are non-redundant proteins in lipid trafficking.
Mon Sep 28 00:00:00 UTC 2020
High-throughput custom capture sequencing identifies novel mutations in coloboma-associated genes: Mutation in DNA-binding domain of retinoic acid receptor beta affects nuclear localization causing ocular coloboma.
Human mutation
Kalaskar VK,Alur RP,Li LK,Thomas JW,Sergeev YV,Blain D,Hufnagel RB,Cogliati T,Brooks BP
R10367 was used in Western Blot to perform custom capture high-throughput screening of 38 known coloboma-associated genes in 66 families.
Sun Mar 01 00:00:00 UTC 2020
EXP1 is required for organisation of EXP2 in the intraerythrocytic malaria parasite vacuole.
Cellular microbiology
Nessel T,Beck JM,Rayatpisheh S,Jami-Alahmadi Y,Wohlschlegel JA,Goldberg DE,Beck JR
R10367 was used in Western Blotting to reveal a novel PVM defect that indicates a critical role for EXP1 in maintaining proper organisation of EXP2 within the PVM.
Fri May 01 00:00:00 UTC 2020
Membrane Protein Dimerization in Cell-Derived Lipid Membranes Measured by FRET with MC Simulations.
Biophysical journal
Škerle J,Humpolíčková J,Johnson N,Rampírová P,Poláchová E,Fliegl M,Dohnálek J,Suchánková A,Jakubec D,Strisovsky K
R10367 was used in Western Blotting to introduce a method to measure surface protein density and to estimate the apparent Förster radius, and use Monte Carlo simulations of the FRET data to account for the proximity FRET effect occurring in confined two-dimensional environments.
Tue Apr 21 00:00:00 UTC 2020
Subnuclear gene positioning through lamina association affects copper tolerance.
Nature communications
Sakamoto Y,Sato M,Sato Y,Harada A,Suzuki T,Goto C,Tamura K,Toyooka K,Kimura H,Ohkawa Y,Hara-Nishimura I,Takagi S,Matsunaga S
R10367 was used in Western Blotting to study the biological function of CROWDED NUCLEI in Arabidopsis thaliana.
Fri Nov 20 00:00:00 UTC 2020
Translational induction of ATF4 during integrated stress response requires noncanonical initiation factors eIF2D and DENR.
Nature communications
Vasudevan D,Neuman SD,Yang A,Lough L,Brown B,Bashirullah A,Cardozo T,Ryoo HD
R10367 was used in Immunocytochemistry to indicate that eIF2D and DENR are critical mediators of ATF4 translational induction and stress responses in vivo.
Wed Sep 16 00:00:00 UTC 2020
Expansion microscopy of C. elegans.
eLife
Yu CJ,Barry NC,Wassie AT,Sinha A,Bhattacharya A,Asano S,Zhang C,Chen F,Hobert O,Goodman MB,Haspel G,Boyden ES
R10367 was used in Immunohistochemistry-immunofluorescence to develop methods of carrying out expansion microscopy on C. elegans (ExCel), in order to map proteins, identify new proteins and analyse gene expression.
Fri May 01 00:00:00 UTC 2020
The SMC5/6 Complex Subunit NSE4A Is Involved in DNA Damage Repair and Seed Development.
The Plant cell
Díaz M,Pečinková P,Nowicka A,Baroux C,Sakamoto T,Gandha PY,Jeřábková H,Matsunaga S,Grossniklaus U,Pecinka A
R10367 was used in Western Blotting to characterise and determine the role of NON-SMC ELEMENT4 paralogs of the SMC5/6 complex in Arabidopsis.
Mon Jul 01 00:00:00 UTC 2019
Synaptic-like Vesicles Facilitate Pioneer Axon Invasion.
Current biology : CB
Nichols EL,Smith CJ
R10367 was used in Immunohistochemistry to visualize the role of synaptic-like vesicles in navigation of dorsal root ganglia pioneer axons.
Mon Aug 19 00:00:00 UTC 2019
Regulation of the apical extension morphogenesis tunes the mechanosensory response of microvilliated neurons.
PLoS biology
Desban L,Prendergast A,Roussel J,Rosello M,Geny D,Wyart C,Bardet PL
R10367 was used in Immunohistochemistry-immunofluorescence to study the morphogenesis and function of sensory microvilliated apical extensions, focusing on cerebrospinal fluid-contacting neurons.
Mon Apr 01 00:00:00 UTC 2019
Tagger-A Swiss army knife for multiomics to dissect cell type-specific mechanisms of gene expression in mice.
PLoS biology
Kaczmarczyk L,Bansal V,Rajput A,Rahman RU,Krzyżak W,Degen J,Poll S,Fuhrmann M,Bonn S,Jackson WS
R10367 was used in Immunohistochemistry to demonstrate that Tagger can capture the desired nucleic acids, enabling multiple omics approaches to be applied to specific cell types in vivo using a single transgenic mouse line.
Thu Aug 01 00:00:00 UTC 2019
Interleukin-6 in the central amygdala is bioactive and co-localised with glucagon-like peptide-1 receptor.
Journal of neuroendocrinology
Anesten F,Dalmau Gasull A,Richard JE,Farkas I,Mishra D,Taing L,Zhang F,Poutanen M,Palsdottir V,Liposits Z,Skibicka KP,Jansson JO
R10367 was used in Immunohistochemistry to study the presence of IL-6 in the central amygdala and the effect of interactions between IL-6 and GLPR-1 in the brain.
Sat Jun 01 00:00:00 UTC 2019
Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca2+ flickers.
Communications biology
Ellefsen KL,Holt JR,Chang AC,Nourse JL,Arulmoli J,Mekhdjian AH,Abuwarda H,Tombola F,Flanagan LA,Dunn AR,Parker I,Pathak MM
R10367 was used in Western Blotting to propose that Piezo1 Ca2+ flickers allow spatial segregation of mechanotransduction events, and that mobility allows Piezo1 channels to explore a large number of mechanical microdomains and thus respond to a greater diversity of mechanical cues.
Mon Apr 20 00:00:00 UTC 2020
Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis.
eLife
Istvan ES,Das S,Bhatnagar S,Beck JR,Owen E,Llinas M,Ganesan SM,Niles JC,Winzeler E,Vaidya AB,Goldberg DE
R10367 was used in Western Blotting to study the importance of Plasmodium falciparum Niemann-Pick Type C1-Related protein activity in the composition of the parasite plasma membrane and digestive vacuole biogenesis.
Tue Mar 19 00:00:00 UTC 2019
SNAREs define targeting specificity of trafficking vesicles by combinatorial interaction with tethering factors.
Nature communications
Koike S,Jahn R
R10367 was used in Immunoprecipitation to conclude that SNAREs use a combinatorial code for recruiting tethering factors, revealing a key function in targeting that is independent of SNARE pairing during fusion.
Mon Apr 08 00:00:00 UTC 2019
Global redox proteome and phosphoproteome analysis reveals redox switch in Akt.
Nature communications
Su Z,Burchfield JG,Yang P,Humphrey SJ,Yang G,Francis D,Yasmin S,Shin SY,Norris DM,Kearney AL,Astore MA,Scavuzzo J,Fisher-Wellman KH,Wang QP,Parker BL,Neely GG,Vafaee F,Chiu J,Yeo R,Hogg PJ,Fazakerley DJ,Nguyen LK,Kuyucak S,James DE
R10367 was used in Western Blot to provide insights into the interplay between oxidative stress-derived redox signalling and protein phosphorylation networks and serve as a resource for understanding the contribution of cellular oxidation to a range of diseases.
Mon Dec 02 00:00:00 UTC 2019
Predominant Golgi Residency of the Plant K/HDEL Receptor Is Essential for Its Function in Mediating ER Retention.
The Plant cell
Silva-Alvim FAL,An J,Alvim JC,Foresti O,Grippa A,Pelgrom A,Adams TL,Hawes C,Denecke J
R10367 was used in Western Blotting to show that ERD2 is exclusively detected at the Golgi apparatus, unlike nonfunctional C-terminal fusions, which also label the ER.
Sat Sep 01 00:00:00 UTC 2018
Label-Free Quantitative Proteomics of Lysine Acetylome Identifies Substrates of Gcn5 in Magnaporthe oryzae Autophagy and Epigenetic Regulation.
mSystems
Liang M,Zhang S,Dong L,Kou Y,Lin C,Dai W,Zhang LH,Deng YZ
R10367 was used in Western Blotting to characterise the comprehensive post-translational modifications executed by Gcn5, in response to various external stimuli, which synergistically promote cellular differentiation in a fungal pathogen.
Thu Oct 01 00:00:00 UTC 2020
Insulin-like Growth Factor-1 Receptor Dictates Beneficial Effects of Treadmill Training by Regulating Survival and Migration of Neural Stem Cell Grafts in the Injured Spinal Cord.
Experimental neurobiology
Hwang DH,Park HH,Shin HY,Cui Y,Kim BG
R10367 was used in Immunohistochemistry-immunofluorescence to study the role of insulin-like growth factor-1 in determining the beneficial effects of treadmill training in transplanted neural stem cells.
Sat Dec 01 00:00:00 UTC 2018
Regulation of Neuronal Na,K-ATPase by Extracellular Scaffolding Proteins.
International journal of molecular sciences
Liebmann T,Fritz N,Kruusmägi M,Westin L,Bernhem K,Bondar A,Aperia A,Brismar H
R10367 was used in Immunocytochemistry-immunoflourescence to study the regulation of neuronal Na,K-ATPase by extracellular scaffolding proteins.
Sun Jul 29 00:00:00 UTC 2018
Loss of embryonic neural crest derived cardiomyocytes causes adult onset hypertrophic cardiomyopathy in zebrafish.
Nature communications
Abdul-Wajid S,Demarest BL,Yost HJ
R10367 was used in Immunohistochemistry to identify a cardiomyocyte population and genetic pathway that are required to prevent adult onset hypertrophic cardiomyopathy (HCM), and provide a zebrafish model of adult-onset HCM and heart failure.
Fri Nov 02 00:00:00 UTC 2018
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.
eLife
Lin JR,Izar B,Wang S,Yapp C,Mei S,Shah PM,Santagata S,Sorger PK
R10367 was used in Immunohistochemistry to develop a tissue-based cyclic immunofluorescence method for highly multiplexed immuno-fluorescence imaging of formalin-fixed, paraffin-embedded specimens mounted on glass slides.
Wed Jul 11 00:00:00 UTC 2018
Nicotine reverses hypofrontality in animal models of addiction and schizophrenia.
Nature medicine
Koukouli F,Rooy M,Tziotis D,Sailor KA,O'Neill HC,Levenga J,Witte M,Nilges M,Changeux JP,Hoeffer CA,Stitzel JA,Gutkin BS,DiGregorio DA,Maskos U
R10367 was used in Immunohistochemistry-immunofluorescence to show that mice expressing a human α5 SNP exhibit neurocognitive behavioral deficits in social interaction and sensorimotor gating tasks.
Wed Mar 01 00:00:00 UTC 2017
A retained intron in the 3'-UTR of Calm3 mRNA mediates its Staufen2- and activity-dependent localization to neuronal dendrites.
EMBO reports
Sharangdhar T,Sugimoto Y,Heraud-Farlow J,Fernández-Moya SM,Ehses J,Ruiz de Los Mozos I,Ule J,Kiebler MA
R10367 was used in Immunocytochemistry-immunoflourescence to identify the retained intron as critical in recruiting Stau2, which then allows for localization of Calm3 mRNA to distal dendrites.
Sun Oct 01 00:00:00 UTC 2017
Circadian rhythms in neuronal activity propagate through output circuits.
Nature neuroscience
Cavey M,Collins B,Bertet C,Blau J
R10367 was used in immunohistochemistry investigate how the activity of a small number of pacemaker neurons is translated into rhythmic behavior of the whole animal
Fri Apr 01 00:00:00 UTC 2016
Sex-specific regulation of Lgr3 in Drosophila neurons.
Proceedings of the National Academy of Sciences of the United States of America
Meissner GW,Luo SD,Dias BG,Texada MJ,Baker BS
R10367 was used in immunohistochemistry to analyze sex-specific regulation of Lgr3 in Drosophila neurons
Tue Mar 01 00:00:00 UTC 2016
A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory.
eLife
Mathew RS,Tatarakis A,Rudenko A,Johnson-Venkatesh EM,Yang YJ,Murphy EA,Todd TP,Schepers ST,Siuti N,Martorell AJ,Falls WA,Hammack SE,Walsh CA,Tsai LH,Umemori H,Bouton ME,Moazed D
R10367 was used in immunohistochemistry to analyze miRNAs up-regulated in the rodent hippocampus upon contextual fear-conditioning and determine that the vesicular transport and synaptogenesis pathways are major targets of the fear-induced miRNAs
Wed Dec 21 00:00:00 UTC 2016
Interaction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicity.
Scientific reports
Kitamura A,Nakayama Y,Shibasaki A,Taki A,Yuno S,Takeda K,Yahara M,Tanabe N,Kinjo M
R10367 was used in Immunocytochemistry-immunoflourescence to characterise aggregation of fluorescently tagged TAR RNA/DNA-binding protein 43 kDa and its carboxyl-terminal fragments, to investigate possible preventive interventions against amyotrophic lateral sclerosis.
Wed Jan 13 00:00:00 UTC 2016
Mechanisms of PDGF siRNA-mediated inhibition of bone cancer pain in the spinal cord.
Scientific reports
Xu Y,Liu J,He M,Liu R,Belegu V,Dai P,Liu W,Wang W,Xia QJ,Shang FF,Luo CZ,Zhou X,Liu S,McDonald J,Liu J,Zuo YX,Liu F,Wang TH
R10367 was used in immunohistochemistry - frozen section to use a herpes simplex virus carrying a small interfering RNA targeting platelet-derived growth factor to alleviate bone cancer pain
Fri Jun 10 00:00:00 UTC 2016
C. elegans Punctin Clusters GABA(A) Receptors via Neuroligin Binding and UNC-40/DCC Recruitment.
Neuron
Tu H,Pinan-Lucarré B,Ji T,Jospin M,Bessereau JL
R10367 was used in Immunohistochemistry-immunofluorescence to show that the Ce-Punctin secreted by GABAergic motor neurons controls the clustering of GABA(A)Rs through the synaptic adhesion molecule neuroligin and the netrin receptor UNC-40/DCC.
Wed Jun 17 00:00:00 UTC 2015
VEGF-B promotes cancer metastasis through a VEGF-A-independent mechanism and serves as a marker of poor prognosis for cancer patients.
Proceedings of the National Academy of Sciences of the United States of America
Yang X,Zhang Y,Hosaka K,Andersson P,Wang J,Tholander F,Cao Z,Morikawa H,Tegnér J,Yang Y,Iwamoto H,Lim S,Cao Y
R10367 was used in immunohistochemistry to demonstrate that VEGF-B promotes cancer metastasis through tumor microvasculature remodeling
Tue Jun 02 00:00:00 UTC 2015
TALPID3 controls centrosome and cell polarity and the human ortholog KIAA0586 is mutated in Joubert syndrome (JBTS23).
eLife
Stephen LA,Tawamie H,Davis GM,Tebbe L,Nürnberg P,Nürnberg G,Thiele H,Thoenes M,Boltshauser E,Uebe S,Rompel O,Reis A,Ekici AB,McTeir L,Fraser AM,Hall EA,Mill P,Daudet N,Cross C,Wolfrum U,Jamra RA,Davey MG,Bolz HJ
R10367 was used in immunohistochemistry to identify and characterize the TALPID3 (KIAA0586) mutation in patients with Joubert syndrome.
Sat Sep 19 00:00:00 UTC 2015
Attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise murine lung repair.
American journal of physiology. Lung cellular and molecular physiology
MacKenzie B,Henneke I,Hezel S,Al Alam D,El Agha E,Chao CM,Quantius J,Wilhelm J,Jones M,Goth K,Li X,Seeger W,Königshoff M,Herold S,Rizvanov AA,Günther A,Bellusci S
R10367 was used in Flow cytometry to show that endogenous Fibroblast growth factor (Fgf)r2b ligands do not significantly protect against bleomycin injury, nor do they expedite the resolution of bleomycin-induced lung injury in mice.
Fri May 15 00:00:00 UTC 2015
Cadherin-6B undergoes macropinocytosis and clathrin-mediated endocytosis during cranial neural crest cell EMT.
Journal of cell science
Padmanabhan R,Taneyhill LA
R10367 was used in immunohistochemistry to study post-translational events that control cadherins during neural crest cell epithelial-to-mesenchymal transition and migration.
Fri May 01 00:00:00 UTC 2015
Digital in vivo 3D atlas of the antennal lobe of Drosophila melanogaster.
The Journal of comparative neurology
Grabe V,Strutz A,Baschwitz A,Hansson BS,Sachse S
R10367 was used in immunohistochemistry to examine the antennal lobe of Drosophila melanogaster
Sun Feb 15 00:00:00 UTC 2015
Regulation of NDR1 activity by PLK1 ensures proper spindle orientation in mitosis.
Scientific reports
Yan M,Chu L,Qin B,Wang Z,Liu X,Jin C,Zhang G,Gomez M,Hergovich A,Chen Z,He P,Gao X,Yao X
R10367 was used in Western Blotting to identify a conserved signalling axis in which NDR1 kinase activity is regulated by PLK1 in mitosis.
Tue Jun 09 00:00:00 UTC 2015
Quantification of Protein Levels in Single Living Cells.
Cell reports
Lo CA,Kays I,Emran F,Lin TJ,Cvetkovska V,Chen BE
R10367 was used in Western Blotting to develop a technique allowing for the in vivo quantification of proteins levels in single cells.
Tue Dec 22 00:00:00 UTC 2015
Conditional ablation of neuroprogenitor cells in adult mice impedes recovery of poststroke cognitive function and reduces synaptic connectivity in the perforant pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Sun C,Sun H,Wu S,Lee CC,Akamatsu Y,Wang RK,Kernie SG,Liu J
R10367 was used in Immunohistochemistry to determine whether depleting neuroprogenitor cells affects post stroke function outcome in mice where expression of a truncated viral thymidine kinase gene and EGFP are restricted to nestin-expressing neuroprogenitor cells.
Wed Oct 30 00:00:00 UTC 2013
The ventral to dorsal BMP activity gradient in the early zebrafish embryo is determined by graded expression of BMP ligands.
Developmental biology
Ramel MC,Hill CS
R10367 was used in western blot to investigate how the BMP activity gradient forms in zebrafish embryos
Sat Jun 15 00:00:00 UTC 2013
Functional labeling of neurons and their projections using the synthetic activity-dependent promoter E-SARE.
Nature methods
Kawashima T,Kitamura K,Suzuki K,Nonaka M,Kamijo S,Takemoto-Kimura S,Kano M,Okuno H,Ohki K,Bito H
R10367 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to engineer a synthetic promoter, the enhanced synaptic activity-responsive element (E-SARE), that drives neuronal activity-dependent gene expression more potently than other existing immediate-early gene promoters.
Sun Sep 01 00:00:00 UTC 2013
Sequential delivery of host-induced virulence effectors by appressoria and intracellular hyphae of the phytopathogen Colletotrichum higginsianum.
PLoS pathogens
Kleemann J,Rincon-Rivera LJ,Takahara H,Neumann U,Ver Loren van Themaat E,van der Does HC,Hacquard S,Stüber K,Will I,Schmalenbach W,Schmelzer E,O'Connell RJ
R10367 was used in immunocytochemistry to identify genes involved in biotrophic and necrotrophic growth of Colletotrichum higginsianum
Mon Aug 20 00:00:00 UTC 2012
The F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently.
Journal of cell science
Coutinho-Budd J,Ghukasyan V,Zylka MJ,Polleux F
R10367 was used in immunocytochemistry and western blot to elucidate the role of F-BAR-domains in cell morphogenesis.
Sun Jul 15 00:00:00 UTC 2012
Exuberant growth and synapse formation of olfactory sensory neuron axonal arborizations.
The Journal of comparative neurology
Marcucci F,Maier-Balough E,Zou DJ,Firestein S
R10367 was used in immunohistochemistry to test if olfactory sensory projections are established in an exuberant fashion.
Thu Dec 15 00:00:00 UTC 2011
