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Invitrogen
TRPM2 Polyclonal Antibody
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Product Details
PA1-24995
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a portion of the human transient receptor potential cation channel, subfamily M, member 2 encoded within exon 25.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
4°C
Shipping conditions
Wet ice
Product Specific Information
PA1-24995 detects TRPM2 from human samples.
PA1-24995 has been successfully used in immunoprecipitation, immunohistochemistry and Western blot procedures.
The PA1-24995 immunogen is a synthetic peptide corresponding to a portion of the human transient receptor potential cation channel, subfamily M, member 2 encoded within exon 25.
Target Information
TRPM2 belongs to the ion transport protein family which includes Sodium, Potassium, Calcium ion channels. This family is characterized by proteins possessing 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. TRPM2 is activated by oxidative stress and confers susceptibility to cell death. Further, TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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