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PA1-25485 detects TRIP6 from human samples. PA1-25485 is expected to cross react with mouse due to sequence homology.
PA1-25485 has been successfully used in Western blot procedures.
The PA1-25485 immunogen is a synthetic peptide corresponding to the region of human TRIP6 encoded within exons 3 and 4.
This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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