Proteintech

TRIM44 Polyclonal Antibody

TRIM44 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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TRIM44 Antibody (11511-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human gliomas using 11511-1-AP (TRIM44 antibody) at dilution of 1:50 (under 10x lens).

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Product Details

11511-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 14 publications 14 publications

Immunohistochemistry (IHC)

View 10 publications 10 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 4 publications 4 publications

Immunoprecipitation (IP)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TRIM44 Fusion Protein Ag2070 (1-334 aa encoded by BC024031)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This is a rabbit polyclonal antibody raised against full length of human TRIM44.

Immunogen sequence: MASGVGAAF EELPHDGTCD ECEPDEAPGA EEVCRECGFC YCRRHAEAHR QKFLSHHLAE YVHGSQAWTP PADGEGAGKE EAEVKVEQER EIESEAGEES ESEEESESEE ESETEEESED ESDEESEEDS EEEMEDEQES EAEEDNQEEG ESEAEGETEA ESEFDPEIEM EAERVAKRKC PDHGLDLSTY CQEDRQLICV LCPVIGAHQG HQLSTLDEAF EELRSKDSGG LKAAMIELVE RLKFKSSDPK VTRDQMKMFI QQEFKKVQKV IADEEQKALH LVDIQEAMAT AHVTEILADI QSHMDRLMTQ MAQAKEQLDT SNESAEPKAE GDEEG (1-334 aa encoded by BC024031)

Target Information

May play a role in the process of differentiation and maturation of neuronal cells. May regulate the activity of TRIM17.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

TRIM44 aggravates cardiac fibrosis after myocardial infarction via TAK1 stabilization.

Cellular signalling

Qian H,Lu Z,Hao C,Zhao Y,Bo X,Hu Y,Zhang Y,Yao Y,Ma G,Chen L

Fri Sep 01 00:00:00 UTC 2023

TRIM44 aggravates cardiac fibrosis after myocardial infarction via TAK1 stabilization.

Cellular signalling

Qian H,Lu Z,Hao C,Zhao Y,Bo X,Hu Y,Zhang Y,Yao Y,Ma G,Chen L

Fri Sep 01 00:00:00 UTC 2023

TRIM44 aggravates cardiac fibrosis after myocardial infarction via TAK1 stabilization.

Cellular signalling

Qian H,Lu Z,Hao C,Zhao Y,Bo X,Hu Y,Zhang Y,Yao Y,Ma G,Chen L

Fri Sep 01 00:00:00 UTC 2023

Cardiac-specific Trim44 knockout in rat attenuates isoproterenol-induced cardiac remodeling via inhibition of AKT/mTOR pathway.

Disease models & mechanisms

Jiang XY,Guan FF,Ma JX,Dong W,Qi XL,Zhang X,Chen W,Gao S,Gao X,Pan S,Wang JZ,Ma YW,Zhang LF,Lu D

Mon May 01 00:00:00 UTC 2023

Cardiac-specific Trim44 knockout in rat attenuates isoproterenol-induced cardiac remodeling via inhibition of AKT/mTOR pathway.

Disease models & mechanisms

Jiang XY,Guan FF,Ma JX,Dong W,Qi XL,Zhang X,Chen W,Gao S,Gao X,Pan S,Wang JZ,Ma YW,Zhang LF,Lu D

Mon May 01 00:00:00 UTC 2023

Cardiac-specific Trim44 knockout in rat attenuates isoproterenol-induced cardiac remodeling via inhibition of AKT/mTOR pathway.

Disease models & mechanisms

Jiang XY,Guan FF,Ma JX,Dong W,Qi XL,Zhang X,Chen W,Gao S,Gao X,Pan S,Wang JZ,Ma YW,Zhang LF,Lu D

Mon May 01 00:00:00 UTC 2023

TRIM44 links the UPS to SQSTM1/p62-dependent aggrephagy and removing misfolded proteins.

Autophagy

Lyu L,Chen Z,McCarty N

Fri Apr 01 00:00:00 UTC 2022

TRIM44 links the UPS to SQSTM1/p62-dependent aggrephagy and removing misfolded proteins.

Autophagy

Lyu L,Chen Z,McCarty N

Fri Apr 01 00:00:00 UTC 2022

Inhibition of SPATS2 Suppresses Proliferation and Invasion of Hepatocellular Carcinoma Cells through TRIM44-STAT3 Signaling Pathway.

Journal of Cancer

Chen L,Yi C,Li W,Tseng Y,Zhang J,Liu J

Tue Jan 05 00:00:00 UTC 2021

TRIM44 mediated p62 deubiquitination enhances DNA damage repair by increasing nuclear FLNA and 53BP1 expression.

Oncogene

Lyu L,Lin TC,McCarty N

Sun Aug 01 00:00:00 UTC 2021

TRIM44 mediated p62 deubiquitination enhances DNA damage repair by increasing nuclear FLNA and 53BP1 expression.

Oncogene

Lyu L,Lin TC,McCarty N

Sun Aug 01 00:00:00 UTC 2021

TRIM44 mediated p62 deubiquitination enhances DNA damage repair by increasing nuclear FLNA and 53BP1 expression.

Oncogene

Lyu L,Lin TC,McCarty N

Sun Aug 01 00:00:00 UTC 2021

MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.

OncoTargets and therapy

Cui D,Wang K,Liu Y,Gao J,Cui J

Sun Apr 17 00:00:00 UTC 2022

TRIM44 is indispensable for glioma cell proliferation and cell cycle progression through AKT/p21/p27 signaling pathway.

Journal of neuro-oncology

Zhou X,Yang Y,Ma P,Wang N,Yang D,Tu Q,Sun B,Xiang T,Zhao X,Hou Z,Fang X

Fri Nov 01 00:00:00 UTC 2019

TRIM44 Promotes Colorectal Cancer Proliferation, Migration, and Invasion Through the Akt/mTOR Signaling Pathway.

OncoTargets and therapy

Li CG,Hu H,Yang XJ,Huang CQ,Yu XQ

Mon Apr 11 00:00:00 UTC 2022

TRIM44 Promotes Colorectal Cancer Proliferation, Migration, and Invasion Through the Akt/mTOR Signaling Pathway.

OncoTargets and therapy

Li CG,Hu H,Yang XJ,Huang CQ,Yu XQ

Mon Apr 11 00:00:00 UTC 2022

TRIM44 promotes human esophageal cancer progression via the AKT/mTOR pathway.

Cancer science

Xiong D,Jin C,Ye X,Qiu B,Jianjun X,Zhu S,Xiang L,Wu H,Yongbing W

Mon Oct 01 00:00:00 UTC 2018

TRIM44 promotes human esophageal cancer progression via the AKT/mTOR pathway.

Cancer science

Xiong D,Jin C,Ye X,Qiu B,Jianjun X,Zhu S,Xiang L,Wu H,Yongbing W

Mon Oct 01 00:00:00 UTC 2018

TRIM44 promotes human esophageal cancer progression via the AKT/mTOR pathway.

Cancer science

Xiong D,Jin C,Ye X,Qiu B,Jianjun X,Zhu S,Xiang L,Wu H,Yongbing W

Mon Oct 01 00:00:00 UTC 2018

TRIM44 promotes human esophageal cancer progression via the AKT/mTOR pathway.

Cancer science

Xiong D,Jin C,Ye X,Qiu B,Jianjun X,Zhu S,Xiang L,Wu H,Yongbing W

Mon Oct 01 00:00:00 UTC 2018

TRIM44, a crucial target of miR-410, functions as a potential oncogene in osteosarcoma.

OncoTargets and therapy

Wang H,Fang ZL,Zhang GH,Ma X

Fri Mar 18 00:00:00 UTC 2022

TRIM44, a crucial target of miR-410, functions as a potential oncogene in osteosarcoma.

OncoTargets and therapy

Wang H,Fang ZL,Zhang GH,Ma X

Fri Mar 18 00:00:00 UTC 2022

Overexpression of TRIM44 is related to invasive potential and malignant outcomes in esophageal squamous cell carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Kawaguchi T,Komatsu S,Ichikawa D,Hirajima S,Nishimura Y,Konishi H,Shiozaki A,Fujiwara H,Okamoto K,Tsuda H,Otsuji E

Thu Jun 01 00:00:00 UTC 2017

Overexpression of TRIM44 is related to invasive potential and malignant outcomes in esophageal squamous cell carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Kawaguchi T,Komatsu S,Ichikawa D,Hirajima S,Nishimura Y,Konishi H,Shiozaki A,Fujiwara H,Okamoto K,Tsuda H,Otsuji E

Thu Jun 01 00:00:00 UTC 2017

Overexpression of TRIM44 is related to invasive potential and malignant outcomes in esophageal squamous cell carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Kawaguchi T,Komatsu S,Ichikawa D,Hirajima S,Nishimura Y,Konishi H,Shiozaki A,Fujiwara H,Okamoto K,Tsuda H,Otsuji E

Thu Jun 01 00:00:00 UTC 2017

Overexpression of TRIM44 is related to invasive potential and malignant outcomes in esophageal squamous cell carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Kawaguchi T,Komatsu S,Ichikawa D,Hirajima S,Nishimura Y,Konishi H,Shiozaki A,Fujiwara H,Okamoto K,Tsuda H,Otsuji E

Thu Jun 01 00:00:00 UTC 2017

TRIM44 promotes proliferation and metastasis in non‑small cell lung cancer via mTOR signaling pathway.

Oncotarget

Xing Y,Meng Q,Chen X,Zhao Y,Liu W,Hu J,Xue F,Wang X,Cai L

Tue May 24 00:00:00 UTC 2016

High expression of TRIM44 is associated with enhanced cell proliferation, migration, invasion, and resistance to doxorubicin in hepatocellular carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zhu X,Wu Y,Miao X,Li C,Yin H,Yang S,Lu X,Liu Y,Chen Y,Shen R,Chen X,He S

Tue Nov 01 00:00:00 UTC 2016

High expression of TRIM44 is associated with enhanced cell proliferation, migration, invasion, and resistance to doxorubicin in hepatocellular carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zhu X,Wu Y,Miao X,Li C,Yin H,Yang S,Lu X,Liu Y,Chen Y,Shen R,Chen X,He S

Tue Nov 01 00:00:00 UTC 2016

High expression of TRIM44 is associated with enhanced cell proliferation, migration, invasion, and resistance to doxorubicin in hepatocellular carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zhu X,Wu Y,Miao X,Li C,Yin H,Yang S,Lu X,Liu Y,Chen Y,Shen R,Chen X,He S

Tue Nov 01 00:00:00 UTC 2016

High expression of TRIM44 is associated with enhanced cell proliferation, migration, invasion, and resistance to doxorubicin in hepatocellular carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zhu X,Wu Y,Miao X,Li C,Yin H,Yang S,Lu X,Liu Y,Chen Y,Shen R,Chen X,He S

Tue Nov 01 00:00:00 UTC 2016

Trim44 facilitates the migration and invasion of human lung cancer cells via the NF-κB signaling pathway.

International journal of clinical oncology

Luo Q,Lin H,Ye X,Huang J,Lu S,Xu L

Mon Jun 01 00:00:00 UTC 2015

Trim44 facilitates the migration and invasion of human lung cancer cells via the NF-κB signaling pathway.

International journal of clinical oncology

Luo Q,Lin H,Ye X,Huang J,Lu S,Xu L

Mon Jun 01 00:00:00 UTC 2015

Trim44 facilitates the migration and invasion of human lung cancer cells via the NF-κB signaling pathway.

International journal of clinical oncology

Luo Q,Lin H,Ye X,Huang J,Lu S,Xu L

Mon Jun 01 00:00:00 UTC 2015

Trim44 facilitates the migration and invasion of human lung cancer cells via the NF-κB signaling pathway.

International journal of clinical oncology

Luo Q,Lin H,Ye X,Huang J,Lu S,Xu L

Mon Jun 01 00:00:00 UTC 2015

Novel function of Trim44 promotes an antiviral response by stabilizing VISA.

Journal of immunology (Baltimore, Md. : 1950)

Yang B,Wang J,Wang Y,Zhou H,Wu X,Tian Z,Sun B

Mon Apr 01 00:00:00 UTC 2013

Novel function of Trim44 promotes an antiviral response by stabilizing VISA.

Journal of immunology (Baltimore, Md. : 1950)

Yang B,Wang J,Wang Y,Zhou H,Wu X,Tian Z,Sun B

Mon Apr 01 00:00:00 UTC 2013

Overexpression of TRIM44 contributes to malignant outcome in gastric carcinoma.

Cancer science

Kashimoto K,Komatsu S,Ichikawa D,Arita T,Konishi H,Nagata H,Takeshita H,Nishimura Y,Hirajima S,Kawaguchi T,Shiozaki A,Fujiwara H,Okamoto K,Tsuda H,Otsuji E

Thu Nov 01 00:00:00 UTC 2012

Overexpression of TRIM44 contributes to malignant outcome in gastric carcinoma.

Cancer science

Kashimoto K,Komatsu S,Ichikawa D,Arita T,Konishi H,Nagata H,Takeshita H,Nishimura Y,Hirajima S,Kawaguchi T,Shiozaki A,Fujiwara H,Okamoto K,Tsuda H,Otsuji E

Thu Nov 01 00:00:00 UTC 2012

Overexpression of TRIM44 contributes to malignant outcome in gastric carcinoma.

Cancer science

Kashimoto K,Komatsu S,Ichikawa D,Arita T,Konishi H,Nagata H,Takeshita H,Nishimura Y,Hirajima S,Kawaguchi T,Shiozaki A,Fujiwara H,Okamoto K,Tsuda H,Otsuji E

Thu Nov 01 00:00:00 UTC 2012

Overexpression of TRIM44 contributes to malignant outcome in gastric carcinoma.

Cancer science

Kashimoto K,Komatsu S,Ichikawa D,Arita T,Konishi H,Nagata H,Takeshita H,Nishimura Y,Hirajima S,Kawaguchi T,Shiozaki A,Fujiwara H,Okamoto K,Tsuda H,Otsuji E

Thu Nov 01 00:00:00 UTC 2012

A 4-gene signature predicts survival of patients with resected adenocarcinoma of the esophagus, junction, and gastric cardia.

Gastroenterology

Peters CJ,Rees JR,Hardwick RH,Hardwick JS,Vowler SL,Ong CA,Zhang C,Save V,O'Donovan M,Rassl D,Alderson D,Caldas C,Fitzgerald RC

Wed Dec 01 00:00:00 UTC 2010

A 4-gene signature predicts survival of patients with resected adenocarcinoma of the esophagus, junction, and gastric cardia.

Gastroenterology

Peters CJ,Rees JR,Hardwick RH,Hardwick JS,Vowler SL,Ong CA,Zhang C,Save V,O'Donovan M,Rassl D,Alderson D,Caldas C,Fitzgerald RC

Wed Dec 01 00:00:00 UTC 2010

Bioinformatics

Protein Aliases: brain cDNA 7; DIPB; DIPB protein; Protein DIPB; Protein Mc7; tripartite motif protein 44; tripartite motif-containing 44; Tripartite motif-containing protein 44

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Gene Aliases: DIPB; HSA249128; MC7; TRIM44

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UniProt ID: (Human) Q96DX7, (Mouse) Q9QXA7, (Rat) Q6QA27

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Entrez Gene ID: (Human) 54765, (Mouse) 80985, (Rat) 362172

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Function(s)

protein binding zinc ion binding metal ion binding

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TRIM44 Polyclonal Antibody

TRIM44 Antibody (11511-1-AP) in IHC (P)

Product Details

11511-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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