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Invitrogen
TNFR2 Monoclonal Antibody (HM102), FITC
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Product Details
MA5-49130
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
HM102
Immunogen
The monoclonal antibody HM102 recognizes the extracellular part of the Tumor Necrosis Factor Receptor type I
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
100 µg/mL
Storage conditions
4°C, store in dark
Shipping conditions
Wet ice
RRID
AB_3093264
Product Specific Information
The antibody is a agonistic receptor modulating antibody. It enhances in vitro TNF alpha responses by increasing the affinity of the soluble form of TNF-alpha for TNF-RII.
Target Information
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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