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Invitrogen
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PA1-21148 detects TNF receptor II in human, mouse and rat samples.
PA1-21148 has been successfully used in immunohistochemistry (paraffin), Immunoprecipitation and Western blot procedures.
The PA1-21148 immunogen is a synthetic peptide to the C-terminal region of mouse TNF receptor II protein.
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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