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Immunogen sequence: KLSTPDVVSPF GTPFGSSVMN RMAGIFDVNT CYGSPQSPQL IRRGPRLWTS ASDQQMTEFS NPSPSTSISA E
Highest antigen sequence identity to the following orthologs - mouse 76%, rat 79%.
TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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