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A suggested positive control is A-20 cell lysate.
PA5-34352 can be used with blocking peptide PEP-1395.
Transmembrane protein 106A (TMEM106A) is a single-pass transmembrane protein that is closely related to TMEM106B, a protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual roles of TMEM106A and TMEM106B are still undetermined; however, as TMEM106B is involved in FTLD, it is possible that TMEM106A may also be a risk factor for FTLD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Transmembrane protein 106A
Gene Aliases: 0610008L10Rik; AI043106; BC022145; TMEM106A
UniProt ID: (Human) Q96A25, (Mouse) Q8VC04
Entrez Gene ID: (Human) 113277, (Mouse) 217203
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