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Invitrogen
TLE Pan Polyclonal Antibody
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Product Details
PA5-17241
Product Specifications
Species Reactivity
Fruit fly,
Human,
Mouse,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues surrounding Asp760 of human TLE1
Conjugate
Form
Liquid
Concentration
261 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10982642
Product Specific Information
It is not recommended to aliquot this antibody.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B lymphocyte gene 1; E(Sp1) homolog; enhancer of split groucho 3; enhancer of split groucho 4; Enhancer of split groucho-like protein 1; Enhancer of split groucho-like protein 2; Enhancer of split groucho-like protein 3; ESG; ESG-1; ESG-2; ESG-3; ESG-4; ESG1; ESG2; ESG3; Grg-1; Grg-3; Grg-4; groucho-related protein; Groucho-related protein 1; Groucho-related protein 4; transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 2, homolog of Drosophila E(sp1); transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 3 short isoform; transducin-like enhancer of split 3, homolog of Drosophila E(sp1); transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 4 (homolog of Drosophila E(spl)) - like; transducin-like enhancer of split 4, homolog of Drosophila E(sp1); Transducin-like enhancer protein 1; Transducin-like enhancer protein 2; Transducin-like enhancer protein 3; Transducin-like enhancer protein 4
Gene Aliases: 2610103N05Rik; 5730411M05Rik; AA792082; BCE-1; BCE1; C230057C06Rik; E(spI); ESG; ESG1; ESG2; ESG3; ESG4; ESTM13; ESTM14; Grg-1; Grg-4; GRG1; GRG2; GRG3; Grg3a; Grg3b; GRG4; HsT18976; KIAA1261; KIAA1547; mKIAA1547; mKIAA4188; TLE1; TLE2; TLE3; TLE4; Tle4l; X83332; X83333
UniProt ID: (Human) Q04724, (Human) Q04725, (Human) Q04726, (Human) Q04727, (Mouse) Q62440, (Mouse) Q9WVB2, (Mouse) Q08122, (Mouse) Q62441
Entrez Gene ID: (Human) 7088, (Human) 7089, (Human) 7090, (Human) 7091, (Mouse) 21885, (Mouse) 21886, (Mouse) 21887, (Mouse) 21888
RNA polymerase II transcription corepressor activity
protein binding
transcription factor binding
identical protein binding
transcription corepressor activity
molecular_function
chromatin binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
repressing transcription factor binding
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
signal transduction
multicellular organism development
organ morphogenesis
positive regulation of gene expression
Wnt signaling pathway
negative regulation of Wnt signaling pathway
negative regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of transcription, DNA-templated
beta-catenin-TCF complex assembly
negative regulation of anoikis
regulation of transcription, DNA-templated
spermatogenesis
cell differentiation
negative regulation of canonical Wnt signaling pathway
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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