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Bioss
TIFA Polyclonal Antibody
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Product Details
BS-13669R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human TIFA, amino acids 51-150.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Putative MAPK-activating protein PM14; Putative NF-kappa-B-activating protein 20; TIFAA; TRAF-interacting protein with a forkhead-associated domain; TRAF-interacting protein with FHA domain-containing protein A; TRAF-interacting protein with forkhead-associated domain; TRAF2 binding protein; TRAF2-binding protein; TRAF6 binding protein
Gene Aliases: T2BP; T6BP; TIFA; TIFAA
UniProt ID: (Human) Q96CG3, (Mouse) Q793I8
Entrez Gene ID: (Human) 92610, (Mouse) 211550
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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