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This target displays homology in the following species: Human: 100%
This gene encodes a protein that regulates thymic epithelial cell proliferation and thymus size. It has been identified as a ligand for the class I human leukocyte antigen (HLA-I) in thymus. Studies of the orthologous mouse protein suggest that it may also play a role in spermatid differentiation, as well as in neuronal morphogenesis and synaptic plasticity. Polymorphisms in this gene are associated with susceptibility for multiple sclerosis (MS). Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Protein SPATIAL; Protein TBATA; Stromal protein associated with thymii and lymph node homolog; Thymus, brain and testes-associated protein
Gene Aliases: C10orf27; SPATIAL; TBATA
UniProt ID: (Human) Q96M53
Entrez Gene ID: (Human) 219793
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