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Invitrogen
Staphylococcus aureus neutral proteinase Polyclonal Antibody
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FIGURE: 1 / 1
Staphylococcus aureus neutral proteinase Antibody (PA5-144507) in WB
Western blot analysis of Staphylococcus aureus neutral proteinase in recombinant protein using a dilution of 1:2,000. Samples were incubated with Staphylococcus aureus neutral proteinase polyclonal antibody (Product # PA5-144507). Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 39.3 kDa. Observed band size: 50 kDa.
Product Details
PA5-144507
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bacteria
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Staphylococcus aureus Zinc metalloproteinase aureolysin (aur) (210-509AA)
Conjugate
Form
Liquid
Concentration
4.18 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% Proclin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3090446
Target Information
Plays an essential role in immune evasion by helping bacteria to resist complement-mediated killing by neutrophils. Inhibits the deposition of host C3b on bacterial surfaces and the release of the chemoattractant C5a by cleaving the central complement protein C3. The cleavage site renders the C3b molecule vulnerable to proteolytic degradation by host regulators (PubMed:21502375). Cleaves and inactivates host SERPINA1, which is an endogenous protease inhibitor essential for controlling neutrophil serine protease elastase (PubMed:3533918). Also plays an essential role in the cleavage and subsequent activation of the serine protease SspA (glutamyl endopeptidase) which is involved in colonization and infection of human tissues (PubMed:17878159).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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