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Invitrogen
Stabilin 2 Polyclonal Antibody
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FIGURE: 1 / 1
Stabilin 2 Antibody (PA5-47522) in Flow
Flow cytometry of Stabilin 2 in K562 human chronic myelogenous leukemia cell line. Samples were incubated in Stabilin 2 polyclonal antibody (Product # PA5-47522) isotype control antibody followed by NorthernLights™ 637-conjugated Anti-Sheep IgG Secondary Antibody.
Product Details
PA5-47522
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant human Stabilin-2 Gly2198-Val2295
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2606336
Product Specific Information
In direct ELISAs, less than 1% cross-reactivity with recombinant human Stabilin-1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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