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Search Thermo Fisher Scientific
Proteintech
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Immunogen sequence: SQEAGTGAG AGSLAGSCGC GTPQRPGAHG SSAAAHRYSR EANAPGPVPG ERQLAHSKMV PIPAGVFTMG TDDPQIKQDG EAPARRVTID AFYMDAYEVS NTEFEKFVNS TGYLTEAEKF GDSFVFEGML SEQVKTNIQQ AVAAAPWWLP VKGANWRHPE GPDSTILHRP DHPVLHVSWN DAVAYCTWAG KRLPTEAEWE YSCRGGLHNR LFPWGNKLQP KGQHYANIWQ GEFPVTNTGE DGFQGTAPVD AFPPNGYGLY NIVGNAWEWT SDWWTVHHSV EETLNPKGPP SGKDRVKKGG SYMCHRSYCY RYRCAARSQN TPDSSASNLG FRCAADRLPT MD (34-374 aa encoded by BC121122)
This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-alpha-formylglycine-generating enzyme 1; FGE; FGly-generating enzyme; Formylglycine-generating enzyme; MGC131853; MGC150436; OTTHUMP00000115300; Sulfatase-modifying factor 1
Gene Aliases: AA543204; AAPA3037; AI463102; AI851573; FGE; PSEC0152; SUMF1; UNQ3037; UNQ3037/PRO9852
UniProt ID: (Human) B7XD05, (Mouse) Q8R0F3
Entrez Gene ID: (Human) 285362, (Mouse) 58911
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