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Invitrogen
STX17 Monoclonal Antibody (GT1252)
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FIGURE: 1 / 1
STX17 Antibody (MA5-27839) in WB
Western blot analysis of STX17 in non-transfected (-) and human STX17-transfected (+) 293T whole cell extracts using 30 µg of protein. Samples were separated with 12% SDS-PAGE and incubated with STX17 monoclonal antibody (Product # MA5-27839) using a dilution of 1:5000.
Product Details
MA5-27839
Product Specifications
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
GT1252
Immunogen
Recombinant protein encompassing a sequence within the center region of human STX17. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.9 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2735375
Product Specific Information
Positive Control: human STX17-transfected 293T
Predicted Reactivity: Mouse (89%), Rat (86%), Rhesus Monkey (99%), Bovine (91%)
Target Information
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. STX17 may also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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