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PA1-30887 detects Somatostatin receptor from rat samples.
PA1-30887 has been successfully used in immunohistochemistry (paraffin tissue) applications. Staining of formalin fixed paraffin embedded tissue sections require high temperture antigen unmasking with 10mM citrate buffer, p.H. 6.0 prior to immunostaining.
The PA1-30887 immunogen is a synthetic peptide derived from the C-terminus of rat somatostatin protein.
Somatostatin acts to regulate numerous physiological processes by binding to and activating specific receptors in target tissues. Activation of these receptors by somatostatin, which is secreted by nerve and endocrine cells, regulates the secretion of insulin, glucagon and growth hormone, neuronal excitability in both the brain and the peripheral nervous system, and cell growth. Somatostatin receptors have been implicated in numerous diseases ranging from Alzheimer's to cancers of the gastrointestinal tract, breast, prostate, and pituitary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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