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Invitrogen
SR-BI Polyclonal Antibody
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FIGURE: 1 / 2
SR-BI Antibody (PA1-16803) in WB
Western blot was performed using anti-SR-BI Polyclonal Antibody (Product # PA1-16803) and a 75 kDa band corresponding to SR-BI was high in Hep G2 when compared to Jurkat, 3T3-L1 differentiated to adipocytes when compared to 3T3-L1; Mouse Liver, Rat Liver and Mouse Testis when compared to Mouse Kidney and Mouse Brain as reported in literatures. Uncharacterized bands (*) were also observed at ~60 kDa, 30 kDa across few samples. Membrane enriched extracts (30 µg lysate) of HeLa (Lane 1), Hep G2 (Lane 2), MOLT-4 (Lane 3), Jurkat (Lane 4), ... View More
Product Details
PA1-16803
Applications
Tested Dilution
Publications
Product Specifications
Published species
Hamster
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the C-terminal residues 400-509 of mouse SR-BI.
Conjugate
Form
Liquid
Concentration
3 mg/mL
Storage conditions
4°C, do not freeze
Shipping conditions
Wet ice
RRID
AB_568737
Product Specific Information
Suggested positive control: mouse liver lysate or protein.
Target Information
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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