Invitrogen

SPATA13 Polyclonal Antibody

SPATA13 Antibody in Immunohistochemistry (IHC)

FIGURE: 1 / 3

SPATA13 Antibody (PA5-25418) in IHC

Immunohistochemistry analysis in formalin-fixed, paraffin-embedded human spleen tissue using a SPT13 polyclonal antibody (Product # PA5-25418), followed by HRP-conjugated secondary antibody and DAB staining.

SPATA13 Antibody in Flow Cytometry (Flow)

Product Image Gallery

Product Details

PA5-25418

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

Flow Cytometry (Flow)

1:10-1:50

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide between 204-232 amino acids from the central region of human SPT13

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Lot-specific

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

AB_2542918

Target Information

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?

Let us know so we can reference it here.

Cite this product

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more