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Invitrogen
SOX21 Polyclonal Antibody
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FIGURE: 1 / 2
SOX21 Antibody (PA5-47505) in ICC/IF
Immunocytochemistry analysis of SOX21 in immersion fixed NTera‚2 human testicular embryonic carcinoma cell line. Samples were incubated in SOX21 polyclonal antibody (Product # PA5-47505) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to nuclei.
Product Details
PA5-47505
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant human SOX21 Ser2-Leu276 (Gly102Ser)
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2576288
Product Specific Information
In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) SOX1, rhSOX2 and rhSOX15 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The SOX gene family is defined by the Sry-related HMG box domain that mediates sequence-specific DNA binding. A variety of functions are associated with the SOX proteins during development. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. SOX21 may play a role as an activator of transcription of OPRM1. Overexpression of SOX21 can cause an up-regulation of the OPRM1 distal promoter in mor-expressing neuronal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SOX-A; SOX25SOX-A; SRY (sex determining region Y)-box 21; SRY box 21; Transcription factor SOX-21
Gene Aliases: SOX21; SOX25; SOXA
UniProt ID: (Human) Q9Y651
Entrez Gene ID: (Human) 11166
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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