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PA1-21544 detects SNX1 in Human samples.
PA1-21544 has been successfully used in Immunocytochemistry and Western Blot procedures.
PA1-21544 immunogen corresponds to Synthetic peptide of human Sorting Nexin 1 encoded within exon 15 (LocusLinkID 6642).
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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