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Abnova
SNTB2 Monoclonal Antibody (3F12)
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Product Details
H00006645-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3F12
Immunogen
SNTB2 (NP_006741.1, 116 a.a. approximately 210 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: VRVVKQEAGG LGISIKGGRE NRMPILISKI FPGLAADQSR ALRLGDAILS VNGTDLRQAT HDQAVQALKR AGKEVLLEVK FIREVTPYIK KPSLV
Target Information
Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin associated protein (DAP) complex formation. To date there have been three distinct syntrophin isoforms discovered: alpha 1, beta 1, and beta 2. These proteins each contain a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a,1b and 2). The PDZ domain has been shown to be responsible for binding syntrophin to nNOS and the DAP complex. This association results in localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 59 kDa dystrophin-associated protein A1 basic component 2; Beta-2-syntrophin; dystrophin-associated protein A1, 59kD, basic component 2; SNT3; SNTL; SYN; syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2); Syntrophin-3; Syntrophin-like
Gene Aliases: D16S2531E; EST25263; SNT2B2; SNT3; SNTB2; SNTL
UniProt ID: (Human) Q13425
Entrez Gene ID: (Human) 6645
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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