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Invitrogen
SMC2 Polyclonal Antibody
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FIGURE: 1 / 1
SMC2 Antibody (PA1-24675) in WB
Western blot analysis of SMC2 using whole cell lysate (90µg) from mock transfected (E) or SMC2 transfected (T) HEK293T cells. Samples were probed with a SMC2 polyclonal antibody (Product # PA1-24675) at a dilution of 0.1µg/ml. Detection was performed using chemiluminescence with a 10 minute exposure.
Product Details
PA1-24675
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a portion of human structural maintenance of chromosomes 2 encoded within exon 22 (LocusLink ID 10592).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
PA1-24675 detects SMC2 from human samples. PA1-24675 is expected to cross react with mouse and Xenopus laevis due to sequence homology.
PA1-24675 has been successfully used in Western blot procedures.
The PA1-24675 immunogen is a synthetic peptide corresponding to a portion of human structural maintenance of chromosomes 2 encoded within exon 22 (LocusLink ID 10592).
Target Information
CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behavior of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in humar cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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