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Invitrogen
SMARCC2 Polyclonal Antibody
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SMARCC2 Antibody (PA5-34838) in IHC (P)
SMARCC2 antibody detects SMARCC2 protein at nucleolus in mouse duodenum by immunohistochemical analysis. Sample: Paraffin-embedded mouse duodenum. SMARCC2 antibody (Product # PA5-34838) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Product Details
PA5-34838
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 85 and 309 of SMARCC2 (Uniprot ID#Q8TAQ2)
Conjugate
Form
Liquid
Concentration
0.67 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
PA5-34838 targets SMARCC2 in WB applications and shows reactivity with Human samples.
The PA5-34838 immunogen is recombinant fragment corresponding to a region within amino acids 85 and 309 of SMARCC2 (Uniprot ID#Q8TAQ2).
Target Information
Cdc73 is a tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. Cdc73 is part of the PAF1 complex, a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9. PAF1 was first purified from yeast in association with RNA polymerase II and is believed to function in transcription elongation. The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. In addition to coordinating events during transcription (initiation, promoter clearance, and elongation), hPAF also coordinates events in RNA quality control. Cdc73 may also be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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