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Invitrogen
SLC4A4 Recombinant Rabbit Monoclonal Antibody (HL1473)
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FIGURE: 1 / 1
SLC4A4 Antibody (MA5-47058) in WB
Western blot analysis of SLC4A4 in Various whole cell extracts (30 µg) separated by 5% SDS-PAGE. Membrane was blotted with SLC4A4 Monoclonal antibody (Product # MA5-47058) using a dilution of 1:1,000 followed by HRP-conjugated anti-rabbit IgG secondary antibody.
Product Details
MA5-47058
Product Specifications
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1473
Immunogen
Recombinant protein encompassing a sequence within the N-term region of human SLC4A4. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2938130
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
Slc4a4 encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Slc4a4 is an electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. Moreover, Slc4a4 may regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. Isoform 2: May have a higher activity than isoform 1. Mutations in the Slc4a4 gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for the Slc4a4 gene. Diseases associated with SLC4A4 include Renal Tubular Acidosis, Proximal, With Ocular Abnormalities and Proximal Renal Tubular Acidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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