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Invitrogen
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Peptide sequence: NTQESLALNS HITGHITGMA SAFRTVYQVG GVTAYFRGVQ ARVIYQIPST
Sequence homology: Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%
Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp547C109; hMRS3/4; Mitochondrial iron transporter 2; mitochondrial RNA splicing protein 3/4; Mitochondrial RNA-splicing protein 3/4 homolog; mitoferrin 2; Mitoferrin-2; MRS3/4; putative mitochondrial solute carrier; solute carrier family 25 (mitochondrial iron transporter), member 28; Solute carrier family 25 member 28; solute carrier family 25, member 28
Gene Aliases: MFRN2; MRS3/4; MRS4L; NPD016; SLC25A28
UniProt ID: (Human) Q96A46
Entrez Gene ID: (Human) 81894
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