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Immunogen sequence: VQSILRFGRHR LNPENRTLGS LRNILYLLHQ RVRRFGIMGL YK
Highest antigen sequence identity to the following orthologs - mouse 93%, rat 93%.
This protein encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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