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Proteintech
SHPRH Polyclonal Antibody
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Product Details
21955-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SHPRH Fusion Protein Ag16635 (1334-1683 aa encoded by BC117686)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EYKLLHEYW MALRNRVSAV DELAMATERL RVRDPREPKP NPPVLHIIEP HEVEQNRIKL LNDKAFATSQ LQKKLGQLLY LTNLEKSQDK TSGGVNPEPC PICARQLGKQ WAVLTCGHCF CNECISIIIE QYSVGSHRSS IKCAICRQTT SHKEISYVFT SEKANQEEDI PVKGSHSTKV EAVVRTLMKI QLRDPGAKAL VFSTWQDVLD IISKALTDNN MEFAQISRVK TFQENLSAFK RDPQINILLL PLHTGSNGLT IIEATHVLLV EPILNPAHEL QAIGRVHRIG QTKPTIVHRF LIKATIEERM QAMLKTAERS HTNSSAKHSE ASVLTVADLA DLFTKETEEL E (1334-1683 aa encoded by BC117686)
Target Information
A novel gene containing SNF2, PHD-finger, RING-finger, helicase, and linker histone domains termed SHPRH, is a possible candidate for a tumor suppressor gene. These domains are characteristic of several DNA repair proteins, transcription factors, and helicases. Mapping of this gene to 6q24, a region reported to contain a tumor suppressor locus suggests a role in tumor suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2610103K11Rik; E3 ubiquitin-protein ligase SHPRH; RING-type E3 ubiquitin transferase SHPRH; SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase; SNF2, histone-linker, PHD and RING finger domain-containing helicase
Gene Aliases: 2610103K11Rik; AA450458; AU024614; bA545I5.2; BC006883; D230017O13Rik; E130018M05; KIAA2023; SHPRH
UniProt ID: (Human) Q149N8, (Mouse) Q7TPQ3
Entrez Gene ID: (Human) 257218, (Mouse) 268281
DNA binding
helicase activity
ubiquitin-protein transferase activity
protein binding
ATP binding
zinc ion binding
ligase activity
ubiquitin protein ligase binding
nucleotide binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
hydrolase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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